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Combine this with so-called "smart transport" molecules?
This is extremely encouraging. I wonder if combining it with some of the technology being developed for next-generation Chemotherapy would be a good next step? The so-called "smart transport" molecules carry a Chemo agent in relatively inert form, and bind with a specific protein found largely on tumors. If one substitutes the anti-CD47 tag for the Chemo agent, now we are (largely) targeting just the tumor, and not opening up the rest of the organism to semi-random attacks.
Posted by drchase
10th Apr 2012