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normal cells don't get taken out
That's a good question, I wondered the same thing. According to the authors, anti-CD47 molecules failed to induce phagocytosis of noncancer cells in vitro. They inferred from this finding that normal healthy tissues lack a secondary prophagocytic 'eat me' signal. So, um, I guess it remains to be seen.
Edited by janetfang
Updated - 10th May 2012