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I wonder what the implications are for removing the PROTECTIVE layer of melanin from the iris? Remember that melanin is deposited in the skin as a protective mechanism to REDUCE damage to the underlying nucleus and its' genetic machinery. People who do not tan as well as others (albinos, those of Celtic ancestry, etc) find themselves at elevated risk for skin neoplasms. The same risks could well apply to the newly Blue-eyed.

A brown eyed Jewish Doc