My significant other and I bought Spider-flex no-nose bike seats last year.
http://www.spiderflex.com/This is what I experienced: It took a while to get it adjusted properly, but once adjusted, was extremely comfortable. No pressure on sensitive areas!! Yes, it feels different compared to a typical bike seat, but just takes a little getting used to.
On my first ride of the season, I have no discomfort, no feeling like I have to build up a "callous" in order to ride comfortably for a distance.
My partner has prostate cancer and was not able to bicycle AT ALL even with a severely centre cut bike seat .. he uses this new seat with great comfort as well and no pain!
