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It's not clear how the mice immune system knew to "self-select" only the cancerous antigens to attack, especially after being injected with DNA from healthy human prostates.

The researchers started with DNA from *human* prostates, and injected them into mice with prostate tumors. Are these special mice that have DNA from humans already? Did their systems view the human DNA as invasive? Injecting human DNA into humans to provoke an immune response may not work as well as injecting human DNA into mice. It's just not clear to me how this works.