By Andrew Nusca
Posting in Cancer
Two research teams have completely sequenced the genomes of people who suffer from genetic disease -- and have come to a surprising twist in our understanding of how it's caused.
Now, two independent research teams have completely sequenced the genomes of people who suffer from genetic disease.
In the first, Baylor College of Medicine's Richard Gibbs sequenced the entire genome of his colleague James Lupski, a medical geneticist who carries the genes for Charcot-Marie-Tooth disease, a nerve disorder.
All three diseases are caused by single, rare mutations in a gene. More common diseases such as cancer are thought to be caused by mutations in several genes.
That goes entirely against the approach scientists have taken toward genetic diseases until now.
Instead, their findings suggest that fully sequencing genomes may instead help researchers explore the roots of common, multi-gene diseases -- and in the case of the family genomes that were sequenced, improving the accuracy of the decoding process.
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Mar 12, 2010
Wake me up when there is a comprehensive test at a fair price (under $300) that tells me everything I need to know to better forecast and anticipate my health needs... and can put it all into an on-line database where I can match up with others around the world to build my family tree. It's basicaly all the same info, yet individual comoanies on the Internet are now charging as little as $500 a pop TO EVALUATE EACH DISEASE. I have seen articles where certain celebrities and were charged in excess of $160,000 for a battery of tests - luidicrous,. But I suppose those celebrities neither care how much they spend of their mega-millions nor have the intelligence to say "That's a stupid idea!" or "WHAAAAAT?!? ARE YOU CRAZY??". The two sides of the coin in stupidity and greed in this world never ceases to amaze me... or maybe it already has.