Posting in Cancer
Everyone knows that smoking causes lung cancer 30 years down the road, but now, scientists are finding is that the process begins almost immediately.
We know smoking cigarettes for years can cause lung cancer, heart disease and a number of other cancers. However, researchers are finding that cigarette smoke can actually damage the body within minutes.
This is contrary to what people believed. Everyone knows that smoking causes lung cancer 30 years down the road, but now, scientists are finding is that the process begins almost immediately.
There are these compounds that have been associated with cancer called polycyclic aromatic hydrocarbons (PAH). The compounds are known to contribute to the onset of lung cancer.
The researchers added PAH to cigarettes to see how the bodies of 12 volunteer smokers reacted. It only took 30 minutes to turn the chemical into one that damages DNA.
Professor Stephen Hecht at the University of Minnesota wrote:
This study is unique, it is the first to investigate human metabolism of a PAH specifically delivered by inhalation in cigarette smoke, without interference by other sources of exposure such as air pollution or the diet.
Essentially, the researchers are finding that inhaling cigarette smoke enters the blood stream so fast that it's like injecting it directly.
The study was published in Chemical Research in Toxicology.
Now, this study was small. It will be interesting to see more studies on PAH, considering this was the first to show how compounds in tobacco can damage DNA.
"The results reported here should serve as a stark warning to those who are considering starting to smoke cigarettes," Hecht wrote.
And of course...it's never to late to quit smoking, one expert said.
Jan 17, 2011
All I can see from reading the paper's abstract is that there is a rapid formation of a PAH-derived known carcinogenic compound in the smoker's blood. It doesn't prove that some cell's DNA is immediately affected, or that cells don't have a way of counteracting the damage most of the time, or that most damaged cells don't simply die And if it's almost certain that once the carcinogenic compound is present in the bloodstream then cells' DNA is damaged, why does it take decades for cancer to form? Even nonsmokers ingest or inhale other carcinogens every day without developing cancer. Obviously, it's a much more complicated path to cancer than is presented here.
"And of course?it?s never to late to quit smoking, one expert said." If the expert is so language challenged as to not know the difference between "TOO late and to quit", and "to late to quit", he should quit talking!
Get over it. This was a bum test. But I agree that people should stop smoking, if for no other reason to protect their lungs.
There is no 2 ways about it, smoking has got to go. Personally, I've had half a dozen family and friends die from causes directly related to it. Several more have persistant medical conditions. Its a lousy habit and has no more to do with "personal freedom" than taking a gun and shooting one's self in the head.
First the FDA tells us Asparatame is safe... it has been shown to damage the brain. Recently the study came out about Flouride in the water supply leading to cancer. Then came the study proving Flouride in water lowers intelligence. We all knew smoking was bad... but now how fast it damages the human body... disgusting! A good way to quit smoking http://smarter-health.com/quit_smoking.shtml Or I guess you can use those e-cigarettes if you don't want to quit. But this latest news is a great reason to quit. To ronnien1 - "lets run a valid tests. Or give us the whole story and not this scaled down scare tactic." And by what criteria would you deem a "valid test"? Who would you want administering such a test? Reading the media release in full, you will see PAH's are already in cigarette smoke. In fact they state "Evidence indicates that harmful substances in tobacco smoke termed polycyclic aromatic hydrocarbons, or PAHs, ..." They added one in particular so they could track it... "Until now, however, scientists had not detailed the specific way in which the PAHs in cigarette smoke cause DNA damage in humans. The scientists added a labeled PAH, phenanthrene, to cigarettes and tracked its fate in 12 volunteers who smoked the cigarettes."
If cigarettes damages the DNA why did they add PAH and not test it without adding. Or are they saying it will alter DNA if you add PAH. I agree we need to stop smoking but lets run a valid tests. Or give us the whole story and not this scaled down scare tactic.
Smoking is extrapolated to almost disappear by the year 2050 and with new information maybe this will happen sooner.