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Scientists grow a brain-like network in the lab

By | June 30, 2011, 4:00 AM PDT

Scientists grew rat neurons on a computer chip, after some time, the cells started to show signs of life. It’s not really a functioning brain, but it does have bursts of neural activity that warrant further investigation. University of Florida researchers think that the brain-on-a-chip experiment could one day be used to stimulate areas of the brain that suffered brain damage from a stroke.

So scientists wanted to see if their method could restore neural pathways. UF professor Thomas DeMarse told Discovery news, that he took regular neurons from an embryonic rat brain, put cells in a dish, and then simulated the effects of a stroke on those cells. Then he mixed in adult stem cells that were tagged with green dye, so he could keep track of the original set of cells and watch how they interacted with each other. The cells were left to grow.

Within 30 days, the cells began to show signs of brain activity. As the neurons begin communicating with each other, a microelectrode array recorded hundreds of neural activity. The scientists saw levels of activity only seen in a developing mammalian brain.

In an earlier experiment in 2004, the UF professor created a living brain of cultured rat cells and showed that it could control a plane. However, this is the first time stem cells had been added to the mix. Growing neurons this way could open up treatments for stroke and other brain conditions. The experiment is still a work in progress though.

But what the UF researchers created is far from a working brain. Just because signs of neural activity occur, doesn’t mean the scientists are close to building an intelligent system.

Artificial brains have long been a central theme in science fiction. Assuming humans are eventually capable of building a synthetic brain, a University of Southern California researcher recently explained to me that a key attribute of a working artificial brain is its ability to demonstrate learning and intelligence. The devices should be able to adapt over time and be smart enough to handle unexpected circumstances. In the future, the applications of a synthetic brain include facial recognitions, vision for autonomous vehicles, robotic rescue missions and treatment for brain trauma.

Brain in a Dish Comes Alive [Discovery News]

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Boonsri Dickinson

About Boonsri Dickinson

Boonsri Dickinson was a contributing editor for SmartPlanet from 2010 to 2012.

Boonsri Dickinson

Boonsri Dickinson

Contributing Editor

Boonsri Dickinson is a freelance journalist based in San Francisco. She has written for Discover, The Huffington Post, Forbes, Nature Biotech, Technewsdaily.com, Techstartups.com and AOL. She's currently a reporter for Business Insider. She holds degrees from the University of Florida and the University of Colorado at Boulder.

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Boonsri Dickinson

Boonsri Dickinson

In the unlikely event that Boonsri has a professional or financial relationship with a company she writes about, it will be prominently disclosed.

She writes for SmartPlanet and is not an employee of CBS.

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The Brain
Great article. Thank you.
Posted by YourFavoriteMartian
30th Jun 2011
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Between science fiction and neuroscience
Our brain is the most complex and unknown part of the human body, yet the the neuroscience has developed a lot in the past decades, and creates science fiction projects like this one. The discovery of the neuroplasticity, the ability of the brain to create and develop neurons and connections to decrease the natural cognitive decline and improve the brain capacity, has also been breakthrough. It created a new form of training - the brain training programs. When scientifically validated, these programs may change your life for the better. I recommend one that is available online, it is for free: CogniFit. http://www.cognifit.com/
Posted by pmlt8973
30th Jun 2011
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Amazing
If they can get something that will get past the damaged areas, the brain often shifts to other areas when it is damaged. So maybe they can create something like a bridge?
Posted by halomar1970
30th Jun 2011
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Azheimer cure
Sounds like a potential cure for Alzheimer, not to mention a quick advanced education. If you augment your brain with additional neurons, the worst part of aging can be avoided.(okay make that second worst). Would you still be human after the last of the original equipment dies?
Posted by felstar@...
1st Jul 2011
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thanks for sharing
Great!!! thanks for sharing this information to us!
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Posted by yarinsiz
Updated - 25th Aug 2011
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