Posting in Finance
The news comes just a week after The New Yorker published a long feature on the causes of obesity, which concluded that larger portions and the human tendency to eat what is put in front of us are big contributors to the rise of obesity over the last 20 years.Now there may be a pill for that.
The dream of everyone who has ever dieted and failed, a simple pill to help you lose weight, has successfully completed a Phase 3 trial and will be submitted to the FDA for approval next year.
(Picture of a small bag of McDonald's Fries from the company's Canadian Web site. If your eyes are very keen you will see a tiny maple leaf on the bag.)
Contrave, from Orexigen Therapeutics of San Diego, was used on over 4,500 and was three times better than a placebo in helping patients lose 5% or more of their body weight. It was also well tolerated, even by diabetics.
Contrave is not the only drug in the obesity pipeline:
- Arena Pharmaceuticals is testing what it calls Lorcasin Hydrochloride, which targets the 5-HT serotonin receptor in the hypothalmus.
- Vivus is testing Qnexa, which combines Phentermine and Topiramate, the latter originally offered as an epilepsy medication.
Shares of Orexigen rose over 20% when news of the success broke.
It's likely that, if FDA approval is granted, the drug will be first tried on diabetics who need to lose weight in order to control their condition, before going out to the general population of the obese.
The news comes just a week after The New Yorker published a long feature on the causes of obesity, which concluded that larger portions and the human tendency to eat what is put in front of us are big contributors to the rise of obesity over the last 20 years.
Now there may be a pill for that, something that convinces you the small bag of fries at McDonald's will satisfy as well as the big box.
Jul 20, 2009
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The last time a drug combination was put on the market,(I am talkinf phen/fen), It wasn't known for a few years that it caused heart and lung problems. I used to weigh 312#'s and am only 5'1". Now I weigh 150-153#'s and have been able to keep it off as well as lose it myself safely. I am type II diabetic and have it under control(A1c was 5.4 in May,09 and lipids in normal range4 also). People need to realize tath there is no miracle drug for weight loss. portion control, exercise and making food an enemy that you only have to have so much of the correct kind of to exist is what works.I know, it worked for me and my husband and we control our BG and lipids with herbs and isupplements.NO SDE effects. Star Shepherd
All drugs have side effects. What serious problems will these new pills introduce down the road? And Type 2 diabetics may be able to use the pills, but Type 1's might be in deep trouble for taking the risk. By the way, what ever happened to good eating habits and exercise. Most coworkers I've know throughout my career have never had weight problems.