Follow this blog:
RSS

The imaginary disease isn’t

By | October 9, 2009, 5:16 AM PDT

Chronic Fatigue Syndrome (CFS), the “yuppie flu” that 1 million people suffer from, which their bosses and some family members insist is imaginary, is probably a viral infection.

(Picture from a 2006 CBS News story on whether CFS exists.)

The virus is called XMRV, it has been found in many CFS patients, and it may also be in the bodies of men who suffer from a virulent form of prostate cancer.

CFS is also called Myalgic encephalomyelitis (ME). Because its cause was unknown CFS has been treated with a number of homeopathic “cures,” including yoga, meditation, and green vegetables.

Scientists at the Whittemore Peterson Institute (WPI) in Reno, Nevada got lucky and identified the retrovirus  in the blood of two-thirds of CFS patients they tested, against just 3.7% of people without the syndrome. A test for XMRV antibodies is now being developed that can provide sufferers with a diagnosis.

The founder and President of WPI, Annette Whittemore, is the mother of a CFS patient. Among the better known sufferers is Laura Hillenbrand, author of the book “Seabiscuit,” from which the popular movie was made.

The link between XMRV and prostate cancer was revealed only last month by Ila Singh at the University of Utah. WPI investigated it because XMRV in prostate cancer patients turned on an enzyme that had been implicated in CFS.

XMRV appears to be a blood-borne virus that may be unlocking other viral mechanisms in the body, some of which cause cancer and others of which are linked to older diseases whose incidence is on the rise.

The most frightening aspect of the new discovery is that the virus may exist in 4% of all people, including millions who show no symptoms but who may not be at greater risk for cancer and other diseases.

Start your week smarter with our weekly e-mail newsletter. It's your cheat sheet for good ideas. Get it.

Dana Blankenhorn

About Dana Blankenhorn

Dana Blankenhorn was a contributing editor for SmartPlanet from 2009 to 2010.

Dana Blankenhorn

Dana Blankenhorn

Contributing Editor, Healthcare

Dana Blankenhorn has written for the Chicago Tribune, Advertising Age's "NetMarketing" supplement and founded the Interactive Age Daily for CMP Media. He holds degrees from Rice and Northwestern universities. He is based in Atlanta.

Follow him on Twitter.

Dana Blankenhorn

Dana Blankenhorn

Dana Blankenhorn has been a technology reporter since 1982, a business reporter since 1978, and a writer for as long as he can remember. His Schwab IRA has a few tech stocks in it, most notably some Intel and Applied Materials bought over 10 years ago. But the vast majority of his tiny fortune (emphasis on the word tiny) is invested in mutual funds. He presently writes for no one else but ZDNet, SmartPlanet and himself. But if you've got an opportunity let him know. If he takes the gig he"ll first add it to this disclosure page.

He writes for SmartPlanet and is not an employee of CBS.

If you liked this, don't miss...
11
Comments

Join the conversation!

Follow via:
RSS
0 Votes
+ -
RE: The imaginary disease isn't
Unfortunately a causal link has not been found but this is a good start.
Posted by Agnostic_OS
9th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
Read more at
http://www.npr.org/templates/story/story.phpstoryId=113650222&ft=1&f=1
00
Posted by Mike106132000@...
12th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
This news appeared in the Wall Street Journal last week. That story included the possibility that the XMRV was a follow-on infection and not the cause of CFS. There is research by Dr. A. Martin Lerner, an infectious disease specialist and long-time medical researcher, that can be found on the Internet that shows that CFS is caused by cytomegalovirus and/or Epstein-Barr virus. Because there are anti-viral drugs specific for these virus, Dr. Lerner hased cured many patients, myself included.
Posted by robertke
12th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
It's good to think, but these early results can't be given so tendentious meaning just yet. Like the other commentator noticed, it could be merely an opportunist pathogen, and this kind of scenario happens more than we'd like for the purposes of isolating causes.

Posted by cameigons
12th Oct 2009
0 Votes
+ -
XMRV is probably NOT a follow-on.
You correct that other viruses may be the direct causes of EM/CFS, but XMRV is likely to be the predecessor (*NOT* the follow-on).

XMRV infects the DNA of white blood cells, and possibly reduces the ability of the body to fight off other viruses. As you describe, one of those OTHER viruses might be the cause of the disease. The rates of infection with XMRV-sourced DNA among EM/CFS pts. in the study is over 50x as high as the rates in the non-CFS population.

IIRC, there are only 3 known retroviruses which infect humans. In the most famous of the other ones, HIV, many people who do carry the virus have not yet presented overt symptoms of disease-- and some, apparently, never will. Some of those non-CFS carriers could perhaps develop the disease in the future.

Huge discovery. I am not one of the researchers, and don't know a great deal about this study yet. But I live in Reno, across the street from one of the study authors wink
Posted by Rick S._z
12th Oct 2009
0 Votes
+ -
Is there a typo in the last sentence?
The structure of your last sentence (the entire last paragraph) makes me wonder if it has a typo. "... but who may not be at greater risk ..." Did you intend "not" to be "now?" That would make a world of difference in the meaning.
Posted by treibs
12th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
Interesting stuff, and tentatively hopeful.

Just a quibble, but your comment regarding 'treated with a number of homeopathic ?cures,?' indicates a lack of familiarity with homeopathy. Perhaps you meant 'holistic', instead.
Posted by dbell@...
20th Oct 2009
0 Votes
+ -
"Homeopathic" isn't a pertinent or 'valid' issue here
considering the basic premise is that one part of active ingredient in 50 million parts, say, of "other" ingredients (less than that, actually, but no need to get totally ridiculous) is supposedly somehow going to be efficacious -- the problem there is that you have absolutely NO way of starting out with 100% pure ANYthing. So your dilutant already includes one part of "everything it has EVER come in contact with" per 50 million parts of dilutant. I.e., we are constantly being bombarded by homeopathic solutions of EVERYthing in our environment, every time we ingest ANYthing. The "noise level" inherent in this means YOUR "homeopathic remedy" is just added to and obscured by the background, meaninglessly.

You believe in "homeopathy", fine. It's a meme. Wash your hands. Thoroughly. Make sure and get rid of that last 0.0000000002%. Don't spread stuff around.
Posted by flared0ne
20th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
CFS has been treated with a number of homeopathic ?cures,? including yoga, meditation, and green vegetables.

Yoga, meditation, and green vegetables have nothing to do with homeopathy. Saying otherwise seriously undermines your journalistic cred--this is very basic stuff.
Posted by rhercz@...
20th Oct 2009
0 Votes
+ -
RE: The imaginary disease isn't
"frightening aspect"..especially when conjoined with "most" blows the journalistic cred without a reader knowing anything at all about yoga, homeopathy or viruses.
it's on a par with saying "the mos frightening aspect of blue eyes is that 20,000 years ago nobody had blue eyes, and neither global warming nor nuclear winter had emerged."
Posted by gabriel bear
20th Oct 2009
0 Votes
+ -
Homeopathy
I have to agree with rhercz: yoga, meditation, and green vegetables aren't homeopathic treatments. They might be considered alternative, which homeopathy certainly is, but they're distinct from homeopathy.
Posted by LeonBA
23rd Oct 2009
Join the conversation
Formatting +
BB Codes - Note: HTML is not supported in forums
  • [b] Bold [/b]
  • [i] Italic [/i]
  • [u] Underline [/u]
  • [s] Strikethrough [/s]
  • [q] "Quote" [/q]
  • [ol][*] 1. Ordered List [/ol]
  • [ul][*] · Unordered List [/ul]
  • [pre] Preformat [/pre]
  • [quote] "Blockquote" [/quote]

Join the SmartPlanet community and join the conversation! Signing up is fast and free. Don't wait -- we want to hear your opinion!