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The celiac epidemic

By | September 30, 2010, 5:55 AM PDT

By looking at collections of blood samples drawn in 1974 and 1989, researchers at the University of Maryland have confirmed something Finnish researchers found out two years ago, that there’s a growing epidemic of celiac disease among the aging.

(Picture of lead researcher Alessio Fasano from the University of Maryland.)

Celiac disease is best understood as an allergy to gluten, the protein that makes pizza and bread dough stretch and rise. If you’re usually getting an upset stomach after eating pizza, pasta, or bread, you might want to be tested for it.

With proper diet it’s no big deal. Lots of famous people have celiac disease, including Saints quarterback Drew Brees, liberal newscaster Keith Olbermann, and conservative commentator Elizabeth Hasselback.

Those names come from the site Gluten Free Kids, because the condition was thought to be lifelong. The lead researcher in this case is a pediatrician by training.

What the research found is not only that celiac disease is rising with age, but that it’s often going undiagnosed. As with lactose intolerance (an inability to digest milk) you may be fine for decades, then develop it.

The treatment is to avoid gluten. Thanks in part to awareness created by kids’ advocates that is becoming easier. You can even get gluten-free hot dogs and beer at a Mets game (although given their play it’s unlikely to prevent stomach upset.)

The key question yet to be answered is why this is happening.

Dr. Fasano thinks this may be due to changes in the bacteria inside your gut. A predisposition to celiac disease may be masked by digestive bacteria, but after they’re killed in later life, by antibiotics used to treat an infection or after surgery, they may just not be replaced. He also wants to look at environmental triggers.

All of which points us to another important avenue of research.

The bacteria in our guts are becoming a much bigger focus of medical research, as Boonsri Dickinson wrote here in June. Their composition differs from person to person, culture to culture, and this population (as many individuals as you have brain cells) may indeed be impacted by things like the use of antibiotics.

Or, as I wrote back in 2008, your colon houses an ecosystem. Respect it. Scientists do.

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Dana Blankenhorn

About Dana Blankenhorn

Dana Blankenhorn was a contributing editor for SmartPlanet from 2009 to 2010.

Dana Blankenhorn

Dana Blankenhorn

Contributing Editor

Dana Blankenhorn has written for the Chicago Tribune, Advertising Age's "NetMarketing" supplement and founded the Interactive Age Daily for CMP Media. He holds degrees from Rice and Northwestern universities. He is based in Atlanta.

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Dana Blankenhorn

Dana Blankenhorn

Dana Blankenhorn has been a technology reporter since 1982, a business reporter since 1978, and a writer for as long as he can remember. His Schwab IRA has a few tech stocks in it, most notably some Intel and Applied Materials bought over 10 years ago. But the vast majority of his tiny fortune (emphasis on the word tiny) is invested in mutual funds. He presently writes for no one else but ZDNet, SmartPlanet and himself. But if you've got an opportunity let him know. If he takes the gig he"ll first add it to this disclosure page.

He writes for SmartPlanet and is not an employee of CBS.

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RE: The celiac epidemic
thank you. I've never heard of this before. Very informative
Posted by gjd
30th Sep 2010
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RE: The celiac epidemic
Per your article, Celiac is an intolerance to gluten not an allergy. There is no anaphylactic response therefore not an allergy.
Posted by gervitsd
30th Sep 2010
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gervitsd
As with lactose intolerance the "cure" is the same as with an allergy, namely avoidance.
Posted by DanaBlankenhorn
30th Sep 2010
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Re: Baseball
Yet another self-hating Mets fan!
Posted by omb00900@...
30th Sep 2010
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RE: The celiac epidemic
"Dr. Fasano thinks this may be due to changes in the bacteria inside your gut."

This sounds logical to me. And it is probably caused by the aluminum used for pots, the teflon on non-stick surfaces we cook with, too many additives in foods, pesticide laced foods, gmo foods, etc.

Basically getting away from healthy food.

But don't worry, big pharma will come up with lots of new drugs you can take so you can live with the disease. Because curing it is not something Western medicine does. Curing a disease is too costly to the drug makers.
Posted by Albee_Freeoneday
30th Sep 2010
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RE: The celiac epidemic
Many children and young adults on the autism spectrum have lab tests and symptoms indicating gastrointestinal disorders including celiac disease. Treatment involves gluten-free/casein-free diets and Specific Carbohydrate diets. Some families have reported the child's regression following vaccine administration, which fits into a theory regarding chronic inflammation. Perhaps some seniors who get vaccinated annually might fall into this susceptible population subset of faulty immune response.
http://www.celiaccentral.org/Celiac-Disease/Related-Diseases/Autism-and-Celiac-Disease/37/
Posted by nhokkanen
30th Sep 2010
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RE: The celiac epidemic
I promise, I'm not trying to stir up anything, this is just an observation/question.

Why did the author seem to find it necessary label Keith Olbermann as "liberal" and Elizabeth Hasselbeck as "conservative"? Why couldn't it have just been "commentator Keith Olbermann" or "TV host Elizabeth Hasselbeck".

I'm only asking because I'm just so worn out by hearing folks being classified by these words. The use seems to stir more arguments than a Cubs/Sox game. Can't they just be left out when its not pertinent to the subject?
Posted by CptMatt
30th Sep 2010
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RE: The celiac epidemic
"Curing a disease is too costly to the drug makers."

Curing a disease would be no more costly than treating the
symptoms. It just wouldn't make the drug companies as much
money.

As long as "the bottom line" is the focus of business, the health
and welfare of people will be ignored.
Posted by pdageek
30th Sep 2010
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RE: The celiac epidemic
I would agree that it isn't necessary to label newscasters. It was nice though to finally see someone labled as "liberal". Conservative newcasters are always labeled.
Posted by wjbowser@...
30th Sep 2010
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Great point gervitsd...
-- Per your article, Celiac is an intolerance to gluten not an allergy. There is no anaphylactic response therefore not an allergy. - -

I know dozens of people who get an upset stomach when they eat particular foods who claim they have an allergy to that food.

Many doctors use the wrong words when telling patients what is wrong with them so people go through life thinking they have an allergy when all that is wrong is intolerance.

One recent study suggested as many as 75 percent of all kids that have been raised being told they are ?allergic? to peanuts actually have an intolerance that is easily manageable.

One local school is trying to charge a bully with attempted murder for smearing peanut butter on the forehead of a kid allegedly allergic to peanut butter. The only injury from the attack was a few scrapes from the plastic knife used to spread the peanut butter.

There was no anaphylactic reaction. Tests are pending to see if the kid is really allergic to peanut butter or if it was a misdiagnosed intolerance.
Posted by Hates Idiots
30th Sep 2010
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RE: The celiac epidemic
Wow great article. I never expected to see this on a tech site. I developed this disease a few years back. I am 27 white male. My diet has always been normal at least I thought it was normal until I got really very sick. Your symptoms you listed make it sound tolerable. For most folks this is worse than chron's disease. It is a very awful disease and makes you very sick and incapable of doing anything when it is at its worst. The doctors thought that I had heart disease then a prostate problem and then. No one wanted to believe it was wheat. My wife and I finally figured it out after cutting everything but rice and vegetables from our diet (she loves me for sure) for an entire month. After realizing it was wheat we start eating products without wheat. A few manufactures make gluten free products but there isn't enough. I became furious when I realize almost everything we ate had gluten protein in it. Even fresh meat like hamburger at the local market could not be trusted. Things like sugar candy and even fluids can contain gluten.

After three years of not eating any gluten. Substituting where ever possible I found myself eating a slice of pizza in New York while on vacation and surprise I did not get sick at all. During my time of not eating wheat I began meeting with alot of people that have studied these strange illnesses. I learned that certain genetics make you predisposed to this disease. I also learned that there were links to both asthma and lactose intolerance (that I both have as well).

It was a danish scientist that I do however believe helped me the most. He told me that our western civilization is obsessed with keeping parasites and bacteria off and more importantly out of our bodies. He said this is totally wrong. Our bodies need invaders to fight against. If our body doesn't have invaders our immune system and the bacteria in our digestive tract will start to attack itself. In our case the gluten protein results in the degradation of the cilia in our intestine (cilia are hair like structures that break down food as it passes by).

He told me that while it might not be acceptable for me to start eating a bowel of parasites each day. There is a massive market for probiotic foods springing up out of the realization that our body's digestive tracts are in trouble. He told me to purposely expose myself and also eat these probiotic foods. I took his advice and 3 years later I can eat gluten again. My cilia have repaired themselves and my life is much more normal. However, I still try to avoid wheat and gluten where possible.

After my "exposure" not only did my gluten allergy subside but my lactose intolerance is gone as well. Something I suffered with 10 years before the gluten issue.

Good luck folks and watch what your eating but also be sure to worry so much if you end up with some dirt in your mouth.
Posted by vamman@...
30th Sep 2010
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RE: The celiac epidemic
As toddlers, my brother and I suffered from celiac disease. The time was the late 1940s. Somehow, our mom and dad were fortunate enough to find, internationally known, Dr. Sidney V. Haas. Dr. Haas was, at that time, devoting extensive research and pioneering contributions to pediatrics, particularly in celiac therapy and the treatment of the hypertonic (colic) infant with atropine.

Dr. Haas is responsible for saving many thousands of children throughout the world by the discovery of the banana diet. In one of his seminal papers (?The Value of the Banana in the Treatment of Celiac Disease,? American Journal of Diseases of Children , October, 1924 ) he said, "Celiac disease is a nutritional disturbance of late infancy and early childhood due to inability to utilize fats and carbohydrates in a normal manner . . . Carbohydrates in the form of ripe bananas appears to be tolerated perfectly, making it possible to bring about a clinical cure in practically all cases.?

Along with a cohort of 598 other children, with celiac, my brother and I were put on the banana diet. Adoption of the diet got rid of the celiac symptoms: stomach bloating with excruciating pain, food non-assimilation, non-elimination, and gross malnutrition. Today, my brother and I no longer suffer from celiac. Prior to Dr. Hass'? discovery of the banana diet, one out of every four celiac patients died, most of the others remained invalids, and only a few recovered. From Dr. Hass? and subsequent researchers and practicioners'? experience, we now know celiac is primarily an intolerance to carbohydrates, and secondarily an intolerance to fats.

Here is a link to some contemporary Research on enzymes for celiac, http://www.enzymestuff.com/conditionceliac.htm#1 . And, this is an excellent web site for information on celiac, http://www.celiac.com . Also, to a certain extent, celiac disease among the aging may be just a perception. It could be a problem of late recognition. This happens with young children, too. Some times, parents of young children believe thier child?s celiac symptoms are from a normal pediatric GI problem and will dissipate and go away all by them selves. An adult, similarly, may continually attribute her celiac symptoms to a nervous tummy, indigestion, ?what I ate, over the weekend,? and so-forth. In any case, examination and treatment is forestalled and the condition worsens. And so, perhaps, the adult, is diagnosed with a case of celiac she developed many years ago, but just came to a painful and dangerous head today.
Posted by rwalker1x
30th Sep 2010
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Question
What does the banana diet entail? Also, does anyone have any ideas for help when I have an "outbreak". Nothing seems to help for the bloating and diarrhea, Immodium AD helps, but I have to take it several times a day when I am having problems. I am currently on day 3 of issues and tired of it! The worst part is that I can't figure out when I had gluten. I thought I had been true to my diet, but something must have snuck in!
Posted by Suebee123
6th Oct
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RE: The celiac epidemic
Dana....

Great article...

I have heard of the gluten problem some people have....Pops up in some of the supplement industry catalogs...Occasionally see it on a food label...

I do not suffer from that condition, or wheat allergy for that matter...So, of course below the radar...

Bananas and probiotic foods...Doable, and probably a good idea anyway...Especially if one has recently gone through an antibiotic regime...
Posted by Mad Axeman
30th Sep 2010
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This can be life-threatening if not caught in time
I have an aunt who didn't discover her celiac disease until her mid-fifties after some of her kids were diagnosed with it. She had long had all kinds of problems that had never been diagnosed.

Unfortunately, she discovered it too late. She is now in her late 70s and is in need of a liver transplant due to celiac complications. She's very weak and close to death. It really is much more than just a food allergy.
Posted by zackers
30th Sep 2010
+1 Vote
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RE: The celiac epidemic
Great conversation on gluten and celiac disease here. I would
point out that what we call celiac is most likely a multitude of
different conditions that respond very well to a gluten free diet.

Some people have immune reactions to gluten, some have
intolerance (inability to properly digest). Intolerance in and of
itself can cause gut dysbiosis.

We also know that gluten can cause leaky gut through zonulin
upregulation.

Bottom line, different people can react in a multitude of ways to
gluten. This video tutorial goes into some greater depth and
detail on the topic:
http://www.glutenfreesociety.org/video-tutorial/gluten-sensitivity-
what-is-it/

All the best,
Dr. Osborne
Posted by docposborne
1st Oct 2010
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Great to hear vamman@...
Shortly after Boston built its first municipal water filtration there was a massive outbreak of stomach issues that could not be traced to any known illness.

A few years later it was determined the water actually got too clean too fast for their bodies. The filtering process was killing helpful parasites and the citizens of Boston needed a few weeks for their bodies to adjust.

One researcher in Boston found this story and has since done successful small trials of using benign tapeworms to treat Crohns disease.
Posted by Hates Idiots
1st Oct 2010
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