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The $50,000 genetic map

By | August 13, 2009, 11:23 AM PDT

One of the great things about following Moore’s Law over my career is watching how things get better and better faster and faster.

Once computers can do something, improvements are rapid. What was a $10,000 big screen TV becomes a $1,000 model, and the less-expensive one is actually better.

The same thing is now happening with gene sequencing. The latest advance: a complete human genome sequenced for about $48,000.

Best of all (from a tech reporter perspective) this was really kind of a publicity stunt, on behalf of Helicos Biosciences, which made the gear that was used. (There it is to the right. It’s called a Heliscope. Cute name.)

The genes sequenced were those of Helicos founder Stephen Quake, a bioengineering professor at Stanford. (Go Cardinal — the color, not the bird.)

To make that price real to you, the first gene sequencing was done in 2003 for $500,000. Last year a genome was sequenced for just $250,000. Now you’re under $50,000, and that includes the labor of the three-person team that did the work.

What does this mean? To Quake, it means that hospitals and even clinics will soon be able to decode your full genome. Notice how fast MRI scanning is growing? That’s a $2 million machine. Imagine how fast this might grow.

From a diagnostic standpoint, it could soon become standard procedure for a doctor stumped based on symptoms to seek a genetic scan and a cause for what ails you. The answer won’t just determine the cost of care, but might tell if you need to have a hard talk with your kids about their future.

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Dana Blankenhorn

About Dana Blankenhorn

Dana Blankenhorn was a contributing editor for SmartPlanet from 2009 to 2010.

Dana Blankenhorn

Dana Blankenhorn

Contributing Editor

Dana Blankenhorn has written for the Chicago Tribune, Advertising Age's "NetMarketing" supplement and founded the Interactive Age Daily for CMP Media. He holds degrees from Rice and Northwestern universities. He is based in Atlanta.

Follow him on Twitter.

Dana Blankenhorn

Dana Blankenhorn

Dana Blankenhorn has been a technology reporter since 1982, a business reporter since 1978, and a writer for as long as he can remember. His Schwab IRA has a few tech stocks in it, most notably some Intel and Applied Materials bought over 10 years ago. But the vast majority of his tiny fortune (emphasis on the word tiny) is invested in mutual funds. He presently writes for no one else but ZDNet, SmartPlanet and himself. But if you've got an opportunity let him know. If he takes the gig he"ll first add it to this disclosure page.

He writes for SmartPlanet and is not an employee of CBS.

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RE: The $50,000 genetic map
I don't know that a genetic scan can be used to diagnose an illness, Two different animals. Genetics can only determine predisposition or in some cases a marker for a genetic disorder that may or may not evolve. The jury is still out on the science. It seems the technology may be far outstripping the "knowledge". This science will take a lot of sampling before we really know what we are looking at, making proper conclusions based on imperical data. But you are right, being able to have a cheap scanning method is the best way to begin amassing a database, a very large datbase. Interesting story.
Posted by wekiva@...
13th Aug 2009
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What genetics can do...
You get a diagnosis, and then you see a genetic marker that predisposes you to the illness. This can have a major impact on how the resulting illness is treated.

Or it can go the other way.

An example from 2007 at ZDNet Healthcare. A genetic testing company executive did a test on himself. It showed he was predisposed to prostate cancer. So he had the test, even though he was younger than the optimal age. That came back positive. He was treated and is with us today. Had he followed common recommendations for testing he might not have been identified for two years, at which point it may have been too late.
Posted by DanaBlankenhorn
14th Aug 2009
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