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Now we know why Ritalin works

By | September 9, 2009, 5:58 AM PDT

Why do stimulants like Ritalin turn ADHD kids normal but turn normal kids into hopped-up screaming meamies?

Turns out it’s all about the dopamine.

Dopamine is a neurotransmitter. It passes signals between cells in your brain. Good signals.

Think of it as a chemical “attaboy.” It is well known as a precursor to adrenaline, and Arvid Carlsson won the 2000 Nobel Prize in medicine for finding this other role.

Recently scientists at the Brookhaven National Lab gave 53 ADHD people and 44 controls a radioactive tracer that would “light up” dopamine receptors and transporters under a PET scanner.

What they found was the ADHD people had fewer of these cells, meaning our brains are less capable of processing dopamine, the chemical “attaboy,” than other people. It’s all gone into the Journal of the American Medical Association.

If you don’t have many cells that process dopamine, the best way to get a healthy dose in your brain is to flood it with chemicals that produce dopamine. Stimulants. That’s why Ritalin and Adderall help ADHD kids. These same chemicals overstimulate a brain with a normal load of dopamine receptors, which is why your kid just gets high on them.

But the study also explains a lot more. Eating stimulates dopamine, so fat ADHDers are self-medicating in the same way as their cousins who try benzedrine or other drugs. So does exercise, which may be why Michael Phelps stays in the pool all day.

This may also be why ADHD “poster boy” Robin Williams reported that, when he used cocaine, he felt quiet, normal, and sane. Cocaine also stimulates dopamine. This may also be why he later became an alchoholic. Alcohol helps stimulate the natural release of dopamine.

This may also be part of what drove Williams to be a comic and actor. Loud applause stimulates dopamine. It may explain why so many other ADHDers are so ambitious, so driven to succeed at their passions. We need more real attaboys to stimulate our limited dopamine receptors.

As an ADHD kid myself, and father to two more, this may also explain something I have found troubling my whole life. I don’t react well to praise. Tell me you like this article and I may just shrug it off. Tell me you hate it and we can have a good argument — well an argument at any rate. Praise doesn’t give me the hit it gives you — I need a lot of it to feel it.

So while some are going to take this study as offering a simple chemical solution to ADHD (more dopamine) I believe therapy is still highly recommended. The real answer lies in self-awareness, using ADHD’s gifts to concentrate and create, while being aware of its downsides and treating yourself more gently as a result.

Word to my fellow ADHDers, of any age, wherever you are. You may not hear the applause, and you may not feel it, but it’s there isif you work hard and listen closely.

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Dana Blankenhorn

About Dana Blankenhorn

Dana Blankenhorn was a contributing editor for SmartPlanet from 2009 to 2010.

Dana Blankenhorn

Dana Blankenhorn

Contributing Editor

Dana Blankenhorn has written for the Chicago Tribune, Advertising Age's "NetMarketing" supplement and founded the Interactive Age Daily for CMP Media. He holds degrees from Rice and Northwestern universities. He is based in Atlanta.

Follow him on Twitter.

Dana Blankenhorn

Dana Blankenhorn

Dana Blankenhorn has been a technology reporter since 1982, a business reporter since 1978, and a writer for as long as he can remember. His Schwab IRA has a few tech stocks in it, most notably some Intel and Applied Materials bought over 10 years ago. But the vast majority of his tiny fortune (emphasis on the word tiny) is invested in mutual funds. He presently writes for no one else but ZDNet, SmartPlanet and himself. But if you've got an opportunity let him know. If he takes the gig he"ll first add it to this disclosure page.

He writes for SmartPlanet and is not an employee of CBS.

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0 Votes
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RE: Now we know why Ritalin works
Don't take this the wrong way but that was very interesting and informative.
Posted by epobirs
9th Sep 2009
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RE: Now we know why Ritalin works
You say kids a lot. Ritalin is very much an adult drug. Any child on it should be watched closely. Other than that great article.
Posted by Greenman76
9th Sep 2009
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RE: Now we know why Ritalin works
I wonder if there is any follow-up on ADHD in childhood (even though it may not have been even called such 60 years ago) and the increasing prevalence of Parkinson's disease in today's senior population. Parkinson's is also a dopamine deficiency disease. As such, it may have a tie in to the same general cause and more important, I wonder if there is a possible use of Ritalin, Cocaine or other drugs to increase dopamine transmission in the brain in the treatment of Parkinson's.

Current Parkinson medications stimulate dopamine generation and/or reduce the break down of dopamine. This sounds similar to Ritalin's action. I wonder if there have been any studies on either using ritallin or other ADHD medications in Parkinson treatment or the converse of using Parkinson drugs in the treatment of ADHD?
Posted by pyrdek
9th Sep 2009
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Wouldn't Ritalin have the opposite effect?
Hi Pyrdek - I believe that by overworking the dopamine system, long term Ritalin use may lead to Parkinson's disease later in life. In one extreme instance, a close cousin of Ritalin was tainted and circulated around San Fransisco in 1983. Called "China White" this synthetic heroine caused a number of unfortunate addicts to acquire Parkinson's after a single dose, due to the MPTP inadvertently present in the drug. While such a dramatic effect would not be expected to occur with Ritalin, it is impossible to predict what could happen long term. That being said, I was given 10-25mg of Ritalin from age 7 until age 16. You can imagine my excitement.
Posted by kimandadam
3rd Apr 2012
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RE: Now we know why Ritalin works
Sorry Mr. Blankenhorn, I still do not believe children, active or not, should
be drugged. If you want to cite science why not include studies on the
development of the human brain, especially in childhood and adolescence.

Also, considering the active marketing of drugs in America, I still wonder
which comes first...the drug or the appropriately labeled "disease".
Posted by KarrasB
9th Sep 2009
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RE: Now we know why Ritalin works
A few years ago I researched the effect Ritalin has on your DNA and found a research group in Galveston Texas that found a change in
DNA was caused by the use of Ritalin. So there is much more to
learn about the effect Ritalin and other drugs of this type effect on
the body.
Posted by ka0mow
9th Sep 2009
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RE: Now we know why Ritalin works
Sorry, KarrasB. When I was a teen, there was no diagnosis or treatment of ADHD. Much like Robin Williams, I found that taking amphetamines did not get me high in the least. It made me feel "normal" and helped me to "fit in" with my peers. When my son was 9 years old, his mother sent him to live with me because he was failing 2nd grade for a second time and she could not handle his behavior. She was suffering from "You won't give DRUGS to my baby" syndrome. When he got here, and after a very lengthy exam, the doctor prescribed Ritalin. It was an absolute miracle and he immediately moved to near the top of his class. Anger and anxiety were replaced by happiness and satisfaction. It's very easy to criticize when you have little or no first hand experience. Giving an ADHD child Ritalin is no different than giving a diabetic child insulin. Or do you oppose that also?
Posted by purevw@...
9th Sep 2009
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Ritalin/Insulin
wrong!! ADHD, is not life or death. People need Insulin to live. Ritalin, is a mind altering drug.
Posted by Drakey86
13th Mar
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RE: Now we know why Ritalin works
My 25 year old daughter has ADHD and I too was very anti-meds until she crashed and burned in the 9th grade. Until then, she had been an A/B student. We had supported her with extra help/tutoring, patience for her accomplishing tasks "differently", and insisting upon her participation in sports because we knew it improved her concentration (but we didn't know why). When the public schools were of no help, we transferred her to a private school for kids who 'learned differently'. It was there that they convinced me to have her re-evaluated by a neurologist. Cutting to the chase: after stablilizing on a small dose of Adderall, she completed high scool in 3 years, graduated with honors, went on to college, and has led a fulfilling, successful life. In her words, "Adderall released the person trapped inside her whole life."

Purevw: I have used the insulin analogy countless times myself. I see no difference either.
Posted by Nancy_GE
9th Sep 2009
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Greenman re: Ritalin
I agree that Ritalin is a powerful drug and should not be given to everyone.

No one should be considered for Ritalin without a pretty firm diagnosis. No one should be on Ritalin who isn't also getting regular talk or behavioral therapy.
Everyone on Ritalin needs to be monitored, not just for side effects and for behavioral changes but because of the physiological changes that happen as we grow. Many teenagers who got relief with Ritalin when they were younger find it no longer works when they get big.

Maybe you thought I was going to disagree with you, but you make a very good point that I think most in the ADHD population understand and agree with.
Posted by DanaBlankenhorn
9th Sep 2009
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Parkinson's and Ritalin
Nothing I've seen in the literature indicates that Ritalin works for Parkinson's.

There are links, however, between ADHD and autism, which is also increasing. Environmental toxins may play a role in that increase, but the doses of mercury in vaccines are insufficient to be the sole cause. Unfortunately there are increased amounts of airborne mercury and mercury in water due to burning of coal for electrical power.
Posted by DanaBlankenhorn
9th Sep 2009
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Belief vs. Science
KarrasB: I don't care whether you believe scientific evidence or not. Science doesn't care. Belief is a completely separate issue.

Science proceeds through hypothesis, experiment, and a new hypothesis. The best experiments ask more questions than they answer. No hypothesis has any value if all it does is answer a big question and is not subject to experimental proof or disproof.

If you want to believe angels dance on the head of a pin go ahead. But extraordinary claims demand extraordinary proof in science.

I don't have to believe in the principles of flush toilets, or believe that germs in water cause disease. That's a key difference. I don't have to believe in Ritalin to now know how it works.
Posted by DanaBlankenhorn
9th Sep 2009
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RE: Now we know why Ritalin works
I was diagnosed with ADD (now ADHD) as a kid and nearly died from using Ritalin that was prescribed to me by my doctor. I can't say that there aren't children or adults that might benefit from such a drug, but from my personal experience, I would agree with the above poster that recommended any parent putting a child on a new drug be very closely monitored and be ready to call an ambulance in case things go wrong. The fact of the matter is that people can react differently to the same medications, so YMMV. Scientists use large populations to find if there is an overall change, not to see if every individual reacts in the same manner (because they don't).

Is the tiny risk of your child dying or becoming addicted and the large risk of side affects worth what ever potential benefit that the drug of your choice offers for you and your child? Meditate on that before you introduce any drug to your children.
Posted by aeriform
9th Sep 2009
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Science vs. Ritalin
There is a large political movement working against Ritalin and other psychoactive drugs, and they sponsor a lot of research. Here are examples -- http://www.icpa4kids.org/research/children/ritalin.htm

However, please note that this latest study only shows why Ritalin works -- the specific mechanism underlying its potential efficacy. There are a wealth of drugs that have been developed for ADHD, and a competent physician can help you find the right path for your child.

In the case of my daughter, by the way, Ritalin was no help at all. Her ADHD manifests itself as dyslexia, a difficulty in decoding words off a page, and turning her thoughts into words from her mouth. Training and accommodation are working for her, however, and she is making it in college.

If you give a kid Ritalin and he tears around the room like he's on speed, you probably need to go another way. Same with an adult.
Posted by DanaBlankenhorn
9th Sep 2009
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Purev's point
Some people respond well to Ritalin and other stimulants for ADHD. It should also be noted that some do not. And our reaction can change over time.

Purev found relief, and says this 9 year old found relief, through the use of Ritalin. One unnecessary byproduct of the anti-Ritalin political movement is to brand otherwise-innocent kids as druggies, or ADHD kids as fakers. I have seen this in my own life. It's abusive.

You don't have to believe in ADHD. You don't have to believe in Ritalin. But competent professionals have developed this diagnosis to explain a range of behaviors, and Ritalin is one of many medications that seem to offer relief for sufferers.

The point of this latest study, again, is to show how Ritalin works, and why it seems to work. More study is always needed.
Posted by DanaBlankenhorn
9th Sep 2009
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Ritalin does not work for everyone
Aeriform: There are mis-diagnoses of ADHD. Ritalin is not advised for all patients, even all ADHD patients. It is among the best tolerated ADHD drugs on the market, the one with the longest history, it's generic and low cost. That's why it's the first choice.

But no one should be given Ritalin and not be monitored. My daughter used Ritalin for only one day, and it did not help her, so that day is now an old family story. There are other solutions.

The key is to keep working for them.

One more point. I don't believe Ritalin or any other psychoactive should be prescribed without therapy and monitoring, both medical and psychological. This makes ADHD more expensive to treat, but I think your example shows why it's necessary.
Posted by DanaBlankenhorn
9th Sep 2009
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RE: Now we know why Ritalin works
A very good article. I have a nephew who suffered (suffers, now, but less) from ADD. He was prescribed Ritalin, and it worked "wonders." He went from being an out of control extrovert to a thoughtful, well-disciplined introvert. He finally became a success at school with his schooling. Yet, despite all the evidence that the Ritalin regiment helped, when he got into middle-school and then high-school, he would often refuse to take the drug. In his words, "it made him not be himself." He not longer had the self-assurance to interact with his peers. And, worse, he felt that he could not be successful with girls.

There was no question that the drug changed his behavior. For the adults in his life, this change was all to the good. However, for this kid, it was a mixed blessing, and he often chose to not take the drug. Now, as an adult, he seems to have overcome some of the worse symptoms, but he is still weary of Ritalin. I guess, like many things in life, medical drugs may offer a fix, but sometimes at a cost.
Posted by roycelcrocker
9th Sep 2009
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RE: Now we know why Ritalin works
Anyone stop to think that drugs for so-called ADHD (aka normal childhood behavior) are STIMULANTS--schedule II drugs in the same category as cocaine, morphine and opium? The DEA says that these drugs are structurally and pharmacologically similar to cocaine. An amphetamine?s chemical structure resembles natural stimulants in the body, like adrenaline. However, as a drug, it alters the natural system and can reduce appetite and fatigue and ?speed? you up. A stimulant refers to any mind-altering chemical or substance that affects the central nervous system by speeding up the body?s functions, including the heart and breathing rates. Between January 2000 and June 30, 2005, the FDA received almost 1,000 reports of kids experiencing psychosis or mania while taking the drugs. On June 28, 2005, the FDA identified possible safety concerns with Ritalin, Adderall, Concerta, etc. Specifically noted were psychiatric adverse effects when prescribed to treat ?ADHD,? such as visual hallucinations, suicidal ideation, psychotic behavior, aggression and violent behavior. So please don't believe everything the psychiatrists tell you to be believe. Find out for yourself, do your homework, and make an informed decision.
Posted by betty09
9th Sep 2009
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Royce L Crocker
It is common that, when children become adolescents, there needs to be an adjustment in medication. They're bigger, the old dose won't work. And they're different, the same drug may stop working.

It sounds from what you write that what the nephew needed, and needs, is therapy, a trusted friend who can help him deal with his problems and prescribe medication when it is needed, but only when the patient is psychologically accepting of it.

That's how ADHD is.
Posted by DanaBlankenhorn
9th Sep 2009
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Betty09
So-called ADHD is a problem.

The problem is people who deny the reality of a condition that afflicts many people, and afflicts children especially because their brains haven't yet developed the self-awareness needed for real social development. (The part of the brain that is trained in kindergarten is, according to CT scans, late in developing among ADHD kids. It does develop, but by that time we're way behind the class in all socialization areas.)

What you have to say about ADHD drugs is one thing. They're drugs and need to be treated with respect -- not handed out like candy. They need to be backed by therapy as well. Every medication has the potential for side effects -- even aspirin.

When you deny the existence of the condition, however, then I have a serious problem. I suffered greatly at the hands of people like you when I was a kid. My kids have suffered from your attitude as well. I am afraid I lack the patience to argue with you. That impatience is part of ADHD, I know, but there's nothing so-called about it.

One personal note. I was diagnosed at age 9 but my mom said "you won't put my kid on drugs." I suffered greatly until I learned what I had, 30 years later. (I take no medication today.) So please don't deny the reality of my life. I'd appreciate that.
Posted by DanaBlankenhorn
9th Sep 2009
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RE: Now we know why Ritalin works
Thank you for a fine article covering this topic. As someone who has struggled with ADD-ADHD, I can tell you from personal experience that stimulants "wake up" the filters in my mind. The filters then help me block out endless distractions which would otherwise keep me from getting *anything* done.

Kids with untreated ADD tend to find their way into cigarettes because nicotine has some properties that work as well.

It's always sad for me to read people using scare-filled language, such as "drugging kids". What really happens is the kid has a difficulty and with meds, they come up to normal.

I always wonder if the people willing to take necessary meds away would be willing to unplug themselves from life-preserving equipment. It's darn near the same thing.

One of my kids has diabetes. He takes insulin for it and would die without it.

Now, let me talk about insulin using the scare-filled language that has shown up in this thread (notably from KarrasB and Betty09):

"Anyone stop to think that drugs for so-called 'diabetes' or 'sugar-sensitivity' (aka normal childhood behavior in snarfing down sugar) are HORMONES -- chemicals so powerful that ONE PART IN ONE BILLION is active?!! The DEA says that the sugar-eaters' drugs are structurally and pharmacologically like many other HORMONES -- like TESTOSTERONE, a Drug ABUSED by Body Builders and which could cause little girls to develop MALE characteristics, and ESTROGEN, a drug essential to the female, but which could cause little boys to develop BREASTS! Imagine the horror for your little guy!

Yes! Between January of 2000 and June 30 of 2005, the FDA received nearly a thousand reports of kids "On HORMONES" ! Especially Teenagers! These kids, while 'buzzed' on HORMONES, typically listen to LOUD ROCK or 'RAP' music which damages their hearing, engage in VERY DANGEROUS behavior such as skateboarding, and they can even say nasty things about YOUR DINNER if it includes BROCCOLI !

You should be alarmed if you see: YOUR CHILD's pants are nearly falling down, YOUR CHILD prefers RAP music to talking with you, YOUR CHILD downloads movies and music, YOUR CHILD loses interest in 2nd year calculus, and of course, YOUR CHILD engages in pre-marital kissing.

Remember: Your Child may be kissing right now WITHOUT YOUR KNOWLEDGE OR PERMISSION! So don't believe everything you've been told to believe. Listen to a doctor with extra training in neurotransmitters (e.g., a psychiatrist). Find out for yourself, do your homework, and make an informed decision.

*grin*

-- Dave
Posted by davetracer@...
9th Sep 2009
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RE: Now we know why Ritalin works
As a non-ADHD father of two ADHD boys (ages 15 and 6), your article really filled in some knowledge hole--good work, not (just kidding). Unfortunately for me, I maybe an undiagnosed ADD kid, no hyperactivity to my "disorder." I remember struggling w/ organization all my childhood. After I entered Navy boot camp is when I really learned how to organize my "stuff", but only after being set back two weeks. I still struggle from time to time usually after a "busy day" with my boys. I agree with you, a combination of therapy and meds is the best way of coping with ADHD for both the kids (meds and therapy) and parents (therapy, parenting education). Best regards.
Posted by drednot57
9th Sep 2009
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ADHD displays in various ways
My son has the typical form of ADHD, which I call "male ADHD." He was diagnosed pretty easily.

My daughter has a different kind, which I call "female ADHD." This displays differently, often alongside a learning disability such as dyslexia. In her case, she has trouble with decoding -- turning letters into sounds and turning the concepts in her head into words.

In a piece I linked to, "The Robin Williams in my Head," I tried to explain this in terms of your reaction to watching Robin in action. The male ADHDer will try to argue with Robin, to top him. The female ADHDer may just watch the show and enjoy it immensely. But her mind is not really in the classroom. She's a good kid but she's not really there.

Also, as noted before, her condition did not respond to Ritalin.

My guess is you don't have ADHD, but getting checked out might be fun anyway. I guess this because you seem to get along with your kids. I have always had problems with my ADHD son -- it's like trying to stick together two north poles of a battery.

And it has always been thus. My dad left me at 18. He left his father at 16. His father kicked his own father out at 16. And that man left Europe, alone, at 15. My son and I are about to set a record....
Posted by DanaBlankenhorn
10th Sep 2009
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DaveTracer
I enjoyed your piece immensely. Rather than getting mad at the people we can't get along with, perhaps it's better to just laugh.
Posted by DanaBlankenhorn
10th Sep 2009
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Some additional information
I need to add here that I have learned some additional facts.

1. About 30% of people without ADD do respond well to Ritalin. I hadn't
known that.
2. Many with ADD do not respond to it.
3. The talk of side effects is real.

No drug like this should be taken without a doctor's prescription, and I
personally wouldn't recommend it except in conjunction with therapy.
Pills can be therapeutic but they're not magic. We have been foolish to
pretend they are.
Posted by DanaBlankenhorn
11th Sep 2009
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RE: Now we know why Ritalin works
If I had been born 10 to 15 years later, they might have diagnosed me with ADD/ADHD as I was a hyperactive child. However, as I had suffered some head trauma during a difficult birth, they thought that I was a borderline epileptic in that, while i had never had a seizure, my EEG was more erratic than other children my age. So they "zonked" me out with Dilantin (an anti-seizure drug) and Librium. For those that don't know, the same chemist first developed Librium, then, years later, Valium and they function in much the same way. Now, imagine giving Librium to an 8th grader and you can guess how much attention they will pay to school.
After falling asleep twice in a geometry class during my sophomore year of high school, I started weaning myself off of the drugs without the doctor's knowledge or permission. While my behavior was more erratic during my last two years of high school, by being more alert, my GPA went up 50 percent.
Ritalin has its place, but, as with any drug, it needs to be closely monitored, not only for its efficacy but for side effects as well.
Posted by JTF243@...
13th Sep 2009
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Agreed. Diagnosis is also tough
JTF: Your story also illustrates the dangers of relying too heavily on a single diagnosis.

It sounds from your story that you came of age in the 1950s. Much has been learned since then, about the brain and about brain chemistry.

We go back-and-forth in this country between reliance on medicine, and reliance on therapy, as solution to our mental conditions. Sounds like you hit another one of the "drug" periods, and that compounded your problem.

My belief is that both drugs and therapy must be tried, and closely monitored. I also think diagnostic work has to be redone from time to time. But that costs money, big money, money that does not exist in enough quantity to deal with all patients.

So we have this patchwork.
Posted by DanaBlankenhorn
14th Sep 2009
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RE: Now we know why Ritalin works
Dana,
The years I mentioned were 1967-72. My parents had taken me to 2-3 different doctors before settling on this one. Staff personnel at a "medical facility" had even suggested the possibility of "shock therapy" (AKA electro-convulsive), despite the fact I had never had a seizure. Fortunately, the doctor over-ruled them.
I went on to get a B.A. in the mid-70's, but I always had problems with retention of data needed for classwork. Even one of my college math instructors, who was tutoring me a little bit, told me one time that he realized I could do the work but that I seemed to "choke" when it came to taking the tests. I still choke on almost any kind of "test". *L*
Posted by JTF243@...
14th Sep 2009
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I used to be very anti-drug for Ad/hd, now I take Adderall
I used to be very outspoken against using stimulants to treat AD/HD in both children and adults. I thought AD/HD was just behavior at an extreme that was really a misdiagnosis.

My own son, in his late high school years, said to us several times that he though he had AD/HD, and I shrugged it off. Finally he got a diagnosis, and treatment, and it did help him.

Several years later, I was watching a TV commercial about AD/HD with my wife, and she turned to me and said, that describes you to a 'T'. I had to agree. I went to a doctor, got diagnosed, got treatment, and it helped me quite a bit. By the way, I'm 56 years old. I wasn't hyperactive, and I didn't have behavior porblems in school. I've owned a series of small software business for over thirty years, but I have been struggling with AD/HD all that time without realizing it.

I've got a grandson, not related by blood, who also has AD/HD, and the difference that Adderall makes for him is dramatic. Taking away his drug treatment would take away his ability to control his life, at least now.

For an AD/HD person without treatment, life is like watching a TV where the channels flips every few seconds, over and over again. For many of us, Adderl, Rialin, or another drug treatment means letting us change the channels when we want to, instead of at random.

Treatment does not have to include drugs for everyone, but I think that for most people, drug treatment at the start is the best option. It helps you see the world the way others experience it, it gives you a normal baseline to work towards.

Once you have the drugs to support more normal brain function, I think it is possible for at least some people to develop skills to deal with the world without the drugs, or at least constant use of them. But that may not be true for everyone.

Are we over-medicating our children? I don't know. But if you don't have AD/HD and you get stimulants, it is not going to improve your experience of life, and I do trust parents and doctors to recognize this.

I wish I had listened to my son when he first told me of his suspicions, instead of relucantly agreeing to his diagnosis and treatment three or four years later.

I understand the strong negative bias against drug treatement for AD/HD, because it was my own opinon for a number of years. I've been reluctantly converted to a different opinon by personal experience.

If you suspect your child has AD/HD, my advice to you as a parent is go get your child tested, and if drug treatment is suggested, try it. You will know within a matter of weeks whether the drugs are helping your child. If not, discus the results with your doctor. Some people respond better to one drug than another. Some may not respond well to any drug. You are not going to turn your child into a drug addict or zombie.

Actually, I think there are some studies to show that kids with AD/HD who get appropriate drug treatment are less likely to abuse other drugs - perhaps because other kids ae trying to self-medicate and untreated condition.

For an AD/HD child without treatment, it's like your child is riding a wild horse without being able to grab the reins. Give your child - or yourself if you have AD/HD - a chance to grab the reins.



Posted by Brad Jensen
15th Sep 2009
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RE: Now we know why Ritalin works
there is such a thing as overfocused add. the focus is on emotional issues usualy, so are not free to focus on other subjects. usualy ritalin will not work for them. there are problems that have add symptoms but are something else: food sensitivities, glucose metabolisim problems, sensiomotor isues, parenting issues, boring teachers, audiotory processing. and others/ a neuroligist will precribe ritalin, and it is likly to help, but it only helps the symtoms, not the problem.
a add coach is very usefull!
Posted by shaul_morgenstern@...
15th Sep 2009
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RE: Now we know why Ritalin works
Article is very informative. I grew up in the 60's and 70's of course they did not have a diagnosis for ADHD. I honestly think that doctors should if they don't test as described in the article to verify a child is ADHD. It may be irrelevant but it seems that the diagnosis they have now is just preliminary and not a final diagnosis. Doctor's I believe should take more care in diagnosing ADHD without physical testing child or adult.
It would be probable today I would have been diagnosed with physical testing that I was ADHD. I had a real bad case of retention although tested with in the mid 60's with a high I.Q.
Interesting my years in elementary, middle school and, high school were passed but never excel (only excelled in sports).
It wasn't till I graduated from H.S. that I realized entering into the military I need to excel and, I did beyond my comprehension. Years after the military I went through job after job, variations of career from law enforcement, retail, office management and, eventually finding my niche. Technology from 1995 to 2004 was my time of retention, discovery. From software support, Tech support, software engineering to finally CIO of a major corporation. Retired now, I don't regret something like ADHD was possibly my diagnosis. I only feel I overcame a hurdle without intervention, on my own. I think children today should be explained the limitation given alternatives and be managed and counseled before being simply said DOPED up. I feel it has become too easy for parents and the medical field to just prescribe rather than work out the problem. Society is too easy to give up... I see this everywhere. Some in thought think it is a developmental issue, I do not. I believe it is still theoretical, non- conclusive. Please understand this is one person?s opinion. I am still discovering myself, learning and, retaining now.
Posted by sidneybarros@...
15th Sep 2009
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RE: Now we know why Ritalin works
I thought that Robin Williams actually had bi-polar
Posted by crine312@...
15th Sep 2009
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RE: Now we know why Ritalin works
And here I was, thinking that Robin Williams had Bi-Polar....
Posted by crine312@...
15th Sep 2009
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Well
Drugs will make you more "normal".

Looking at the state of thins, I wonder if we do them a dis-service.
Posted by jrbwalk@...
15th Sep 2009
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RE: Now we know why Ritalin works
Would you please repeat that?
Posted by chobersdeert@...
15th Sep 2009
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I have ADHD
had been 1st gen diagnosed. Ritalin wasn't avail to me then. It was Stellazine, Norpramine, Novaine, and Lithium. Nasty cocktail when put all together. All of em were consider anti-psychotics. Now everyone knows is best based on us guinea pigs who mad this happen for the newer gens to take hold. My life is no diff than then, I just know how to control it better. Age did that, and the fact I disn't want to not be in control anymore
Posted by LapDRx
15th Sep 2009
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RE: Now we know why Ritalin works
@dave - great reply. Very apropos to turn their logic around.

The reason most people are against ADD/ADHD meds is that the entire disorder is misnamed. It is really irritating. As a successful adult, i was recently diagnosed after doing about a year of research on my own to try and understand my concentration and priority issues.

The thing that really confused me at first and most other people is that i have the ability to hyper-focus. Just like i think most ADHDers do. The disorder should really be called Executive Function Disorder.

I don't always have the Executive Function to focus on the appropriate things. And if i hyperfocus on the wrong thing i can "snap out of it" an hour later and realize i lost track of time.

It really makes sense though. It's easy to focus on things that create a dopamine response. Exciting things are easy to focus on.

Don't you think Arguments create the same physiological response that stimulants do? What about risk-taking activities?

For all the people that are "anti-drug," maybe you should consider taking away glasses, contacts, crutches, wheelchairs, and braces away from your kids? Drink coffee in the morning? Shame on you for needing drugs!

Posted by focksmartplanet
15th Sep 2009
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RE: Now we know why Ritalin works
Omega-3s does wonders to balance out our suite of neurotransmittters. I was ADHD and bipolar (still am as those are permemant traits that can ohly be managed well or poorly), and taking and eating high-quality fish (oils) has done wonders. it's easier to focus and think. mood is more event. it brings balance back to life. sadly, it's pretty cheap and the economics are such that it doesn't really make anyone monies to market this in the US at least so it is bread and butter stuff which works but get shortchanged in the press and everyday conversation. so here I am doing my small part.
Posted by awakeinwa
15th Sep 2009
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dopamine and Parkinson's
ADHD and Parkinson's not the same, but they do both involve dopamine pathways.
In Parkinson's, I believe it's been traced to failure to convert the melanin stored in
the substanta nigra into dopamine, due to lack or low level of an enzyme. The
reason levo-dopa treatments worked for a short while, is that they drove up the
dopamine levels. Unfortunately, the person's homeostasis can then cause
receptors to be removed from service, as it were, to get back to what it "believes"
is the "normal" state of lower satisfaction signals. This is also seen when SSRIs
are used, but I haven't seen any such problem happening with Ritalin or Adderal.
But some teachers known they can sometimes get an ADD child to calm down by
giving him a cup of coffee.
Posted by Professor8
15th Sep 2009
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re: other possibilities
This article caught my attention since I've spent a lot of time in the last couple years reading about ADHD. My 7 year old daughter was initially diagnosed as having ADD, after her school complained about her inability to concentrate and refusal to follow instructions in the classroom. (At home, it was a little more difficult to confirm or deny the school's issues, since the home environment was much different than the classroom; only the 2 of us at home vs. a whole class full of kids around her age and less structured.) But I definitely noticed she was a very active kid (hyperactive, some might say - while others would insist that she was just "a normal, but very active and curious kid").

Honestly, the first psychiatrist I had her visit, I had no confidence in. He branded her with the ADD diagnosis after only spending 3-5 minutes with her and quickly skimming some of the notes the school gave us. His initial plan was to try some experimental things, including a blood-pressure lowering medication that was supposedly shown in at least one small trial to help ADD/ADHD in a percentage of the kids tested. (It seemed to show some promise initially, but after 2 weeks or so, I'd say she returned to her normal behavior.)

In the meantime, I found quite a bit of information on the Internet about childhood bi-polar disorder, and much of it sounded like it could describe her pretty well. (This seemed like an even greater potential possibility because my ex-wife was diagnosed as bi-polar.) When I gave all my printed out research to the psychiatrist, he immediately prescribed lithium for her! I hesitantly tried that for a short time (along with regular blood tests they required to go along with it), and it seemed to have no effect.

At this point, I tried a 2nd. psychiatrist, who acted like the lithium and bi-polar diagnosis was "way out in left field" and went back to the ADD/ADHD idea, prescribing Adderall XR. We tried that for several months, and the daily reports I got home from her school were really mixed. On one hand, they seemed to believe she was doing better, now that I finally "listened to their suggestions" and put her on medication -- but at home? I saw no consistent changes in her behavior. I finally took her off the medication for a while (not telling the school), and the reports still indicated she was "doing better with the medication".

Finally, I had her tested at a local center specializing in autism disorders, and they concluded after an 1 1/2 hour long test that she actually had Asperger's Syndrome! (They didn't rule out the possibility that she *also* had ADD and/or ADHD, but indicated that many Asperger's kids are falsely diagnosed as ADD/ADHD because some of the symptoms are so similar.)

This qualified her to go to class in the special school district, where she's enrolled in a classroom that handles kids with similar issues. It seems like she's doing much better since then, without any medications involved I have a feeling a big part of this may simply be her growing up and getting more mature, though, too.

The more I read about all of these disorders, and the more parents I meet with kids suffering from them, the more I'm convinced that they're all more alike than different. Some of these diagnoses given seem like splitting hairs, and in some cases (like "childhood bi-polar"), I can find quite a few psychiatrists who don't even believe it exists, while others say it does, but young kids are developing too rapidly for it to be ethical to attempt treatment that early, and of course still others say it's treatable and SHOULD be diagnosed and treated as young as age 4 or 5.

With my daughter, I'm glad I'm not giving her any medications right now, even if it's arguable they do her *some* small measure of good in the short-term. I really think that if such treatment is necessary, it will become clearer only as she gets older and can express her feelings and emotions in a more advanced way.
Posted by kingtj
15th Sep 2009
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I can't get the drug that works for me...
ritalin and adderall give me panic attacks, when I was a kid I took
dexadrine, after taking that I understand how some people accomplish
so much. With that I could do anything, now I find it difficult to
concentrate on anything that I don't find utterly fascinating.

I self medicate through frequent use of alcohol and sex. Trust me, it's
no life to lead. All drugs, especially aphetamine based drugs, should be
CAREFULLY monitored. They can cause a healthy individual sever
brain damage and should NEVER be taken recreationally. But to tell a
kid he has to find a way to self medicate can lead to DANGEROUS
behaviours that will take them a lifetime to recover from, THAT is worse
than them taking a drug. All decisions regarding the health of your child
should be consulted with more than one profesional and considered and
prayed about before taking action (meditation if you don't believe in
prayer)
Posted by shadfurman
15th Sep 2009
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self medicating
see natural remedies below. i can almost guarantee that it will work if you will do it.
Posted by mo thompson
20th Jul
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RE: Now we know why Ritalin works
These wonder drugs are a cash cow for Big Pharma.
www.cchr.org
Posted by macdonald00@...
15th Sep 2009
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Sidney Barros
The first concentrated diagnosis and treatment of ADHD was done at
Purdue in the early 1960s. I was diagnosed in 1964, but my mom rejected
the diagnosis. (You're not putting my kid on drugs.)

I know about Purdue because my son's teacher in elementary school,
Joan Teach, did some of that original diagnostic work while a grad student.
Posted by DanaBlankenhorn
15th Sep 2009
+1 Vote
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natural remedies
I want to second some of the natural remedies (it's not really a
comment about the article, but some of the commenters might find it
interesting)

I have tried and seen a small benefit from, again this is what I
personally have done and only give the amount I took as an indicator
that I was taking more or less than a regular amount

Omega complex supplements (8 count dose)
Vitamin B complex supplements (4 count dose)
(costco sells a balance of vitamins called focussmart, 4 count)
St. Johns Wort (4 count)
Salvia leaf (unconcetrated, smoked)
Time released caffine

There are many other "natural" remedies, these are the only ones I
found had any effect for me. Unfortunately none of these really work
that well, and some seem to cancel each other out.


Posted by shadfurman
15th Sep 2009
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natural remedies
this is essentially a list of things needed by the body to stimulate dopamine. excellent advice.
Posted by mo thompson
20th Jul
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Kingtj
The most important asset an ADHD kid can have is a parent who is
willing to work as hard as you do and try to get things right. The actual
diagnosis is a lot less important than finding relief from the symptoms,
and there are many avenues available -- diet is one, therapy a second,
drugs a third.

The focus of drug therapy is to get relief from the symptoms. If you're
not getting relief on Ritalin, you may be among the 30% of ADDers who
don't respond to stimulants.

On a personal note, your child will bless you one day. Just don't expect
it to be any time soon. My son still doesn't get along with me. He's 18
Posted by DanaBlankenhorn
15th Sep 2009
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Shadfuhrman
Ritalin doesn't work in 30% of cases. That goes for all stimulants. But
there are some non-stimulant medications available, and other avenues
worth exploring.

ADHDers do tend to self-medicate. I did, in young adulthood, stopping
some years before I learned of my diagnosis.

I have no argument with trying "natural" supplements, but all chemical
formulae -- whether manmade or "natural" -- are chemical formulae. So
all the warnings we offer on drugs should be made on other chemicals.
If you're getting relief check for side effects (gills?).

I have been recommended to take more Omega 3 recently, but it is for
my ongoing heart condition -- high cholesterol runs in my family like
ADHD does.
Posted by DanaBlankenhorn
15th Sep 2009
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CCHR
CCHR stands for the "Citizens Committee for Human Rights," an anti-
psychiatry group that calls psychiatry "an industry of death."

There are adverse reactions to all drugs, by the way, not just those
impacting the mind. There are people who don't respond to stimulants
yet have ADHD.

But to call psychiatry "an industry of death" is to paint with a broad
brush, in a provocative way, an entire class of people who are dedicated
to serving people and helping them find relief -- by a variety of means --
to what ails them. It's prejudice.

There is a lesson here. Mental health is a scary subject. Treatments
are expensive and they don't always work. Mental health diagnosis and
treatment is far behind physical diagnosis and treatment, with regards
to success rates and accuracy.

That's no reason to give up.
Posted by DanaBlankenhorn
15th Sep 2009
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dangerous psychiatry
again, people with what i call "filter disorders" are generally intelligent. the message here is, do your own research. know why you're taking what you're taking, and look for the most natural solution.
Posted by mo thompson
20th Jul
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