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Lab-on-a-chip is the hot trend in diagnostics

By | August 11, 2010, 6:40 AM PDT

Of all the medical breakthroughs emerging from research labs today, none seems likely to have such an impact on how health care is delivered than the Lab on a Chip.

(Picture of researcher John McDevitt from CNET, by Jeff Fitlow at Rice University.)

Companies as large as IBM, to LabNow in Austin, Texas, to start-ups are commercializing systems that can diagnose a variety of diseases in the field, or in a doctor’s office.

People like John McDevitt, now at Rice University, are creating the tests, with input from subject matter experts like Martin Thornhill, a British tissue researcher.

McDevitt, who was previously at UT-Austin, calls his work the “integrated bio-nano chip,” because biologic agents and small sensor chips are combined on a single slide.

The revolution is that tests can now be done at the point of care, inside a computer that fits into a backpack.

Many aspects of this are also subject to the economics of Moore’s Law — as they go into mass production costs go down. The basic LabNow device is already priced at just $250.(I got that wrong. The link is to a report on the device, which costs about $250.)

(UPDATE: McDevitt writes to say he expects instrument costs to drop 80% and test costs by 50% from present levels using this technology.)

This also means that researchers can create start-ups that deliver specific tests for the LabNow, much as software companies developed in the wake of the IBM PC. Throat cancer — there’s an app for that.

Tests for various diseases, whether in poultry or people, become applications on a standardized platform.

Much of the publicity about LabNow involves the ability to truck it into remote areas and do tests for diseases like AIDS. But the real revolution is in low-cost testing that can be done in a doctor’s office.

Instead of having a physician send a blood sample to, say, Quest Diagnostics, analysis on specific diseases can be done the way a pediatrician today tests for strep throat.

Whenever my kids went to their pediatrician with a cough and cold symptoms, the strep test was his first thought. It was cheap, it was quick, it was results while-you-wait.

Now imagine this being done for AIDS or cancer. Imagine a medical clinic having a host of these slides, every nurse trained to collect swabs and test them,  instant answers to questions we now agonize over for weeks, a treatment regimen chosen during your first office visit.

The impact of this on the system should not be underestimated. Entire industries and hospital specialties have been built over the last decades to do what this simple machine can do in a matter of minutes.

The industries and specialties won’t disappear. They will evolve. But gradually they will be worn down, and diagnostics over the next 10 years will move from the back line to the front line of medical care. And at much lower cost.

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Dana Blankenhorn

About Dana Blankenhorn

Dana Blankenhorn was a contributing editor for SmartPlanet from 2009 to 2010.

Dana Blankenhorn

Dana Blankenhorn

Contributing Editor

Dana Blankenhorn has written for the Chicago Tribune, Advertising Age's "NetMarketing" supplement and founded the Interactive Age Daily for CMP Media. He holds degrees from Rice and Northwestern universities. He is based in Atlanta.

Follow him on Twitter.

Dana Blankenhorn

Dana Blankenhorn

Dana Blankenhorn has been a technology reporter since 1982, a business reporter since 1978, and a writer for as long as he can remember. His Schwab IRA has a few tech stocks in it, most notably some Intel and Applied Materials bought over 10 years ago. But the vast majority of his tiny fortune (emphasis on the word tiny) is invested in mutual funds. He presently writes for no one else but ZDNet, SmartPlanet and himself. But if you've got an opportunity let him know. If he takes the gig he"ll first add it to this disclosure page.

He writes for SmartPlanet and is not an employee of CBS.

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RE: Lab-on-a-chip is the hot trend in diagnostics
Are you sure the device is $250? From the link, it looks like a report
on the company is $252.
Posted by jtdavies
11th Aug 2010
+1 Vote
+ -
PDF report on company is $252, not BioChip device
The company's major product is the CD4 BioChip system. Its products are currently not available for sales.

Initial commercialization efforts are focused on a simple to use system that includes a versatile, compact analyzer and single-use, disposable BioChips for point-of-care testing of critical blood parameters associated with HIV/AIDS.
Posted by gmeader
11th Aug 2010
+1 Vote
+ -
RE: Lab-on-a-chip is the hot trend in diagnostics
I got the $250 data from a page linked from Google shopping. If I
erred I can correct it. But the device itself isn't that complicated, in a
computing sense.

It's a razor blade.The money is in the blades.
Posted by DanaBlankenhorn
11th Aug 2010
+1 Vote
+ -
RE: Lab-on-a-chip is the hot trend in diagnostics
How many clinical laboratory tests can this device analyze at one time and how many chips will it take to do say a CMP? Lyle.
Posted by Ivan_Zell
12th Aug 2010
+1 Vote
+ -
RE: Lab-on-a-chip is the hot trend in diagnostics
How many clinical laboratory tests can this device analyze at one time and how many chips will it take to do say a CMP?
Posted by Ivan_Zell
12th Aug 2010
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