Posting in Cancer
The financial impetus of finding a baldness cure could finance an important line of cancer research.
My line is a familiar one. Grass doesn't grow on a busy street. And my wife's father went bald early, too, so she's not bothered about it.
Hair loss is genetic. Genes that cause hair loss can come from the mother or the father. A genetic pathway for turning hair growth off-and-on was recently discovered in Sweden. It has long been believed that hair could be a target for gene therapy.
Our 18 year old son is worried. He has a full head of lustrous red hair, long enough to wear in a big, thick ponytail. What's in his future?
Maybe, hair. A team under Angela Christiano (above, not follically-challenged) at Columbia University in New York has found that a mutation in the APCDD1 gene, which lives on chromosome 18, inhibits the Wnt signaling pathway that can turn hair growth on-and-off.
This is important, Dr. Christiano says, because "we have years of beautiful data in our field about hair growth in mice," and this matches it, meaning the mouse data can be brought to bear in the search for cures. The key is the Wnt (pronounced wint) signaling pathway:
"Manipulating the Wnt pathway may have an effect on hair follicle growth -- for the first time, in humans," said Dr. Christiano. "And unlike commonly available treatments for hair loss that involve blocking hormonal pathways, treatments involving the Wnt pathway would be non-hormonal, which may enable many more people suffering from hair loss to receive such therapies."
Now before you start making that old Seinfeld line about the dermatologist not being a real doctor, Wnt signaling pathways have also been implicated in many cancers, and new targets for drugs aimed at it have been recently identified. The field is big enough to have its own community of researchers.
More research money could speed things along, and baldness could be a source of that money.
Thus the financial impetus of finding a baldness cure could finance an important line of cancer research.
Apr 15, 2010
While there are certainly more important things out there that genetic engineering could help with, I'm glad to see progress being made for baldness. Sure it'll be too late to help me, but maybe my son can benefit from this if he needs to (or my grandkids, for that matter). Besides, I imagine this is an easy topic to get money for the research (since there's a lot of money in hair & baldness), and discoveries made here might help with breakthroughs in less well-funded but more critical areas, such as Tay-Sachs Disease. I know nobody's commented yet asking why we're going after something as "trivial" as baldness, but in case anyone did wonder that, I wanted to put this out there.
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Actually that's not how women see it. It's how men do. If all women were looking for was a thick head of hair in a man, the supply of baldies would drop to zero.
One thing I've noticed is that in all the pictures I've seen of men who've managed to make it into their 100s, not a single one of them is a chrome dome. They all seem to have at least a few wisps of hair left at the top of their heads.
And, as for the "fashion choice", rest assured that baldness will NEVER be seen by women as anything other than a loss of youthful vigor. Dream on. That day will never come.
Why the non-capitalization of the first letter of the first word in your sentences. It causes me to suspect you are some kind of a nut, although your ideas and grammar are otherwise quite sound. If you want to be taken seriously in such forums as these, I respectfully recommend that you follow established standards of written English.
Yeah always there was found some genetic reasons in cancer including some research statement. here providing good information about genetic research on cancer. www.cancery.com
I notice that Dana has a similar setup to me - very little on top plus a beard. If I go to the barber, the cost of having my beard trimmed is 60% cheaper than the haircut, even though there is (at least) 60% more hair on my face than on my head. Work that one out, if you can!
Being follicley challenged(politicly correct term for being bald in the UK) as was my father and grandfather which is not a problem does not save on barbers bills as stated, the reason being it still grows at the side and back.Although I have pointed this out to many barbers while asking for a discount the say that the search fee for remaining hair offsets the discount for lack of hair so the price remains the same.....
Why? I mean, I'm looking forward to the day when my baldness is a fashion choice, a sort of reverse Mohawk. I like not getting hair in my eyes, and it saves on barber bills.
The cure for baldness is still a long way off.My late father said that if it were possible The duke of Edinburgh (UK queens husband) and prince Charles,who have loads of money would by now have long flowing hair....
for those who rant against research that is acaemic in character, i.e. not tied to some specific need nor purpose, this research is the reason it is so valuable. there is no limit to what other important things might be discovered. this is especially true when dealing with such a complex thing like the human animal. baldnes for some is important but for most people it is trivia and ignored except for the wearing of a hat in the sun one might also understand that the whole electronics industry now supplying people with all those little gadgits came about because we decided we were going to spend very large amounts of money to do that really silly thing of putting a man on the moon.