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How to make acupuncture a hundred times more effective

By | April 23, 2012, 10:09 AM PDT

Mark J. Zylka, a neuroscience researcher at the University of North Carolina at Chapel Hill, admits he had never thought much of Chinese medicine. But when he needed a better delivery method for pain relief drugs, he came across some acupuncture research that caught his eye.

Traditional acupuncture needles can stimulate the release of nucleotides in our body that convert into adenosine, which makes us less sensitive to pain. Unfortunately, that break from hurt typically lasts just a few hours.

Zylka had been working with prostatic acid phosphatase (PAP), which also makes adenosine in the body. When injected into the spine, it can provide up to three days of relief from pain. But, spinal injections are invasive and have to happen in a hospital setting, making them impractical for anyone but those in excruciating pain.

Noticing the adenosine connection between acupuncture and PAP, Zylka wondered if he might be able to co-opt the ancient practice to deliver the protein. Zylka explains in a press release:

“We knew that PAP makes adenosine and lasts for days following spinal injection, so we wondered what would happen if we injected PAP into an acupuncture point? Can we mimic the pain relief that occurs with acupuncture, but have it last longer?”

His team injected PAP in typical acupuncture fashion behind the knee. Zylka found the method so successful it outlasts the pain relief of traditional acupuncture one hundred times over, providing up to six days of relief. It also lasts longer than a dose of anesthetic. He published his results today in the journal Molecular Pain.

So far Zylka’s studies of PAP and acupuncture have all been in mice, so he needs to refine the technique for humans.  He calls the it “PAPupuncture”, and hopes it can one day provide a less invasive way, longer-lasting treatment to replace traditional anesthesia.

Photo: Gemma Vittoria/Flickr

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Audrey Quinn

About Audrey Quinn

Audrey Quinn is a contributing editor for SmartPlanet.

Audrey Quinn

Audrey Quinn
Contributing Editor

Audrey Quinn is a multimedia science journalist based in Brooklyn, New York. She has corresponded for PRI's The World, Radiolab, Deutsche Welle's Living Planet, and a number of NPR affiliate stations. She also produces and hosts a podcast for the Mind Science Foundation. Previously, she performed neuroscience research at the University of Washington Autism Center and the Seattle VA Hospital.

Follow her on Twitter.

Audrey Quinn

Audrey Quinn

Audrey does not have financial holdings that would influence how or what she covers.

She writes for SmartPlanet and is not an employee of CBS.

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accupuncture
Many people have a misconception on how acupuncture works. Why do you insert a sharp needle for what reason? If you can answer this question scientifically then a whole new world opens up for the treatment with acupuncture not necessarily with a sharp needle. The whole issue turns around the increase in blood flow. Factors to be taken into account, Blood type and pH balance. Remember Dr Andrew Stanway from the U K states in his book "Alternative medicine" on acupuncture that nobody knows how it works not even the people in the East, but work it certainly does. Further he states that acupuncture works for only 80% of patients. Knowing why and how acupuncture works you can, with additional treatment, secure a 100% treatment.

Santapiet
Posted by santapiet
24th Apr 2012
0 Votes
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accupuncture and Chinese medicine
Most of people on earth do not know much about Chinese medicine. Accupuncture is a small extension of Chinese medicine. Theory is existing but subject to interpretation becuse most practicioners do not have enough background. For example why accupuncture would work for 80% is because the "shift of quie" not accupture joint. I bet 10 people in the whole USA would know about this. If they do not know, what do you expect accupuncture would work for you?
Posted by chinmanwong@...
25th Apr 2012
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Acupuncture
Aloha,
Acupuncture is part of a complete system of health and healing that has worked for thousands of years.While this new procedure intrigues me, I am wary of a use for acupuncture that in all of these years, the Chinese have not used.Since the Chinese Revolution, Eastern and Western medicine have been embraced. I would think that someone would have tried this before now.Moxa would be the closest thing to injecting a substance in an acupuncture point.
www.newjumpwing.com
Posted by pdnman@...
24th Apr 2012
0 Votes
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Has Quinn ever received acupuncture?
She writes, "Unfortunately, that break from hurt typically lasts just a few hours." I've been getting acupuncture treatments for my knee for 9 months now and have experienced not only long-lasting pain relief, but also no more fluid accumulation on my knee. Typically, I don't experience improvement until a day or two after the treatment. Sometimes it seems to get worse for a day or two before a marked improvement. I don't see how using acupuncture needles to deliver drugs would be an advantage to those of us who turned to acupuncture to stop pumping drugs into our bodies.
Posted by saaut
28th Apr 2012
0 Votes
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Nucleotide content of food = acupuncture effectiveness?
Perhaps we should also look at our dietary intake of these wonderful pain dulling nutrients, namely nucleotides. This could be a way of making acupuncture even more effective at pain relief for IBS sufferers. Some foods naturally contain high levels of nucleotides, offal, meat, fish, and yeast extracts hold the greatest content. Unfortunately, the Western diet generally does not include much offal, such as liver, kidneys and tripe. Such foods are predominant in the diet of the countries, such as China, where acupuncture is used as a front-line treatment. Could the higher content of nucleotides in the diet of people in the Far East be one of the main reasons why acupuncture is so effective and therefore so predominent in the Far East?
Posted by rhnnl
22nd May
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