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Heal wounds with spray-on skin

By | August 5, 2012, 10:39 AM PDT

If you’re weak of stomach, this may not be the article for you. We’re going to talk about leg ulcers - sores that happen when high blood pressure in your leg veins causes your skin to break down into an open wound.

Doctors typically treat leg ulcers with compression bandages. But those only heal about 70% of ulcers, after six months of treatment, says BBC News. They can also graft skin from another part of your body over the sore, but that procedure causes another wound in the area of the removed skin and the grafts take a while to prepare.

A group of American doctors figured there had to be a better treatment option for leg ulcer sufferers. They developed a spray of engineered tissue. The spray coats wounds with a combination of newborn skin cells and fibroblasts, connective tissue cells that coordinate healing.

They reported in the journal The Lancet this week that leg ulcers began rapidly decreasing in size following application of the spray. Patients showed the most healing when they received the spray every 14 days, and 70% of their wounds healed after three months.

The researchers say further study is needed to determine the practicality of the treatment, but at this point they argue that the initial high cost of the spray is outweighed by the money saved through faster healing.

[via BBC News]

Photos: Andrew Magill/Flickr and veinsveinsveins.com

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Audrey Quinn

About Audrey Quinn

Audrey Quinn is a contributing editor for SmartPlanet.

Audrey Quinn

Audrey Quinn
Contributing Editor

Audrey Quinn is a multimedia science journalist based in Brooklyn, New York. She has corresponded for PRI's The World, Radiolab, Deutsche Welle's Living Planet, and a number of NPR affiliate stations. She also produces and hosts a podcast for the Mind Science Foundation. Previously, she performed neuroscience research at the University of Washington Autism Center and the Seattle VA Hospital.

Follow her on Twitter.

Audrey Quinn

Audrey Quinn

Audrey does not have financial holdings that would influence how or what she covers.

She writes for SmartPlanet and is not an employee of CBS.

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-4 Votes
+ -
Spray on Skin
It seems that you only heal 70% either way. At least "fetus's" don't have to die when using compression bandages.
Posted by Ronald Warshall
6th Aug
-3 Votes
+ -
Draw the Line
This science stems from cells made available through wicked acts, but where do you draw the line? These scientists are most likely not performing abortions, but they are using this evil to try to create something to heal. When children and adults are murdered, that does not stop us from using their organs and tissue, is this also evil?

The issue here does not lie with scientists who use whatever is at their disposal to attempt to create something great, the issue is that our country allows abortion. Let's get back to the root of this and stop it there. Let's go after real criminals, like Planned Parenthood (487 million in tax money received in 2010, over 300000 abortions).

One observation on the above article, the statement "initial high cost of the spray is outweighed by the money saved through faster healing" shows the mindset of the company creating it. There is no mention of what is better for the patient. There is no humanity left in medicine, it is just business, despicable.
Posted by notevolution
6th Aug
+2 Votes
+ -
Spray on skin
"The new treatment is a form of cell treatment applied as a spray. It contains keratinocytes, which are the main cell type in the outer layer of the skin, and fibroblasts, a cell type found in connective tissue. These cells had been grown in the laboratory and were originally derived from newborn foreskin samples (removed during circumcision)." http://newsfeedresearcher.com/data/articles_m32/ulcers-wound-treatments.html
Do your research before you jump to conclusions.
Posted by jptpa
6th Aug
0 Votes
+ -
Question and observations.
In a graft situation is there a reason why the persons own skin cells cannot be harvested and grown as they do for burn patients? The grown cells could be used to graft the original injury and the donor site.

The only advantage of this treatment over compression bandages is a faster time to heal. The actual recovery rate is the same for both treatments.

There are other options beyond conventional compression bandages that the article leaves out.

http://www.betterhealth.vic.gov.au/bhcv2/bhcarticles.nsf/pages/Leg_ulcers?open

Even this, made from the persons own cells, could be an option. If it works on burns, why not here?

http://www.smartplanet.com/blog/smart-takes/printed-skin-cells-to-treat-burns/28142
Posted by Hates Idiots
Updated - 6th Aug
+1 Vote
+ -
Where did aborted fetuses come into play?
At NO point, was it stated babies were killed. It stated it was circumcized tissue, which is when foreskin is removed from the end of a penis. Geez!

Even if fetus tissue IS used, it's not like people are aborting humans. They abort a comglomeration of cells that may or may not form into something even remotely resembling a human months down the road. Women's bodies eject unfertilized eggs every month, but do we stone them to death because they didn't have sex with some dude and turn what could have been a baby into a baby?

At certains points, it is NOT okay to rip a baby out of someone's womb because it is too developed, but if it's just a few cells that don't even resemble something remotely human, with no brain development, etc., why does it matter? ...And if it DOES matter, then why aren't we arresting women who don't have sex every month before their period does exactly what an abortion does? Afterall, potential life is potential life, right? Just because their egg hasn't been fertilized yet, doesn't mean it can't be fertilized. So now women are required to have sex every hour of every day of every month until their egg is fertilized. Periods are illegal, and screw overpopulation because THAT'S not an issue since we have to bring every possible human into the world that we can no matter the consequences or circumstances of the pregnancy. That's our priority! Every possible baby... EVER!!! And STONE the women who don't want to go along with it. Hell, they DESERVE to be raped if they're going to let their eggs go bad every month, right?
Posted by brandonkelton
6th Aug
+1 Vote
+ -
Avita Medical
An Australian company Avita Medical already has a spray-on skin on the market in Europe and elsewhere selling as " ReCell " , and is currently undergoing FDA approval. ReCell uses the patients own tissue to generate new skin cells.

http://hotcopper.com.au/announcementFiles/2012/AVH/0525c6dd-203a-43f1-bb1a-3c64f5e29d74-AVH590783.pdf
Posted by yarraberb
6th Aug
0 Votes
+ -
venus leg ulcers
I am a leg wound sufferer. This would be my 2nd summer with 2 leg ulcers. This time not so severe. However the pain, this time moved into my calf muscle. I had started briefly with an Unna Boot. My doctors recently went on summer vacation. I was taken off the Unna Boot. Put on Medi-honey and Lotrimin 1%. Itching so severe was thinking about going to the Emergency room. The Lotrimin was 100% in effective. I had a small amount of Fluocinonide 0.05% cream. I covered the whole area with it. I got a new prescription for it the next day. The itching stopped immediately. I researched Fluocinonide. It shrinks swelling around leg wounds. The itching no more. The itching from leg wounds is crazy. That cream along with the honey and a support stocking worked like a miracle. I don't need to go back to the wound clinic. I think sufferers and doctors need to know about this. This a comfortable way to heal leg wounds. Real cheap too! I hated the Unna Boot. I washed the wounds 2 to 3 times a week and changed the honey. I applied the Fluoc cream morning and night. As they have gotten better I began to apply the cream directly on the wounds. Then the honey. Then the sock. It has worked. The dry spots like eczema are 70% gone. This is awesome stuff.
Posted by stevers47
1st Sep
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