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Back pains? Brain scans predict how long they’ll last

By | July 3, 2012, 7:08 PM PDT

A new technique can predict which patients with sore backs will end up enduring it as chronic back pain.

According to a new study, there’s a difference in brain scans between two groups of patients – those whose pain subsides and those whose pain lasts for years. And this difference appears early in the course of the pain.

By analyzing the scans, researchers were able to predict whether the patients would develop chronic pain with an 85% level of accuracy – leading to ways of identifying patients who are the most at risk and to new treatments or preventions.

“Chronic pain is one of the most expensive health care conditions in the US, yet there still is not a scientifically validated therapy for this condition,” says study researcher Vania Apkarian of Northwestern University.

  1. Over the course of a year, his team tracked 39 patients who reported back pain.
  2. They scanned the patients’ brains four times and followed their pain.
  3. While 20 patients recovered during this time, the pain persisted in 19.
  4. The team then looked at a number of brain characteristics, including the amount of communication between two areas of the brain previously seen to have altered activity in back pain patients: the insula and the nucleus accumbens. (These regions are involved in emotional responses to a person’s environment and in how the brain learns.)

They found more communication between the two areas in chronic back pain patients than in those whose pain subsided. And the increased crosstalk could be seen as far back as the start of the study, ScienceNOW reports, suggesting that it could have predicted which patients would suffer the whole year.

The findings also suggest that brain regions involved in learning and emotions are important in the development of chronic pain – and not just brain regions directly responsible for sensing pain.

“This is the very first time we can say that if we have two subjects who have the same type of injury for the same amount of time, we can predict who will become a chronic pain patient versus who will not,” Apkarian says.

And drugs could be developed to dampen the communication between the brain areas to treat or prevent chronic pain.

The work was published in Nature Neuroscience this week.

[Via ScienceNOW, US News and World Report]

Image by Andreanna Moya via Flickr

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Janet Fang

About Janet Fang

Janet Fang is a contributing editor for SmartPlanet.

Janet Fang

Janet Fang
Contributing Editor

Janet Fang has written for Nature, Discover and the Point Reyes Light. She is currently a lab technician at Lamont-Doherty Earth Observatory. She holds degrees from the University of California, Berkeley and Columbia University. She is based in New York.

Follow her on Twitter.

Janet Fang

Janet Fang

Janet does not have financial holdings that would influence how or what she covers.

She writes for SmartPlanet and is not an employee of CBS.

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0 Votes
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Back Pains Article
This is addressed to all those who either have read or know the progress of this new potential treatment. Will this have any affect for those of us who have been diagnosed with arthritis of the spine where nerve blocks have been unsuccessful?
Another question I have is wii this treatment have any effect on millions of people who suffer from disc herniation in the neck may subside when other non surgical treatments like nerve blocks have failed?
One last question to the author is has this treatment been used on any chronic migraine headache patients to see if it improves their situation?
I appreciate any response and have suffered from all the of the above for years. I can be reached phc1519@gmail.com. Thank you for any responses..... Phil

Tho
Posted by phc1519
4th Jul
0 Votes
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This is addressed to all those who either have read or know the progress
I do not think this applies to a predetermined clear physical cause, as shown on x-ray Only to unknown or undiagnosed pain with no apparent clear cut reason.
Posted by ronangel
6th Jul
+1 Vote
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id most at risk = no more insurance ??
Just wondering, if these scans are predictors of those at most risk, will health insurance companies ber able to use these in order to kick you off their plans, or worse, to never issue you a plan in the first place?

can employers end up using them or requiring them during pre-employment physicals to make hiring decisions? especially if their health insurers coerce companies to minimize such risks by refusing to hire such people?

the idea of getting proper treatment - and early treatemebt - is wonderful! but I fear the unintended consequences!
Posted by rivardau
4th Jul
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Insurance
You very well know that insurance companies will be the first ones to abuse this medical technology. I wouldn't be surprised to learn that the insurance companies are the ones funding this research....
Posted by Tinman57
6th Jul
0 Votes
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the cause of the pain...
I luckily never had chronic pain, but did have severe back pain at least once a year. I just wanted to recommend Esther Gokhale's solution. She teachs posture as 'traditionally' practiced in Africa and other places. If you're interested, search for a video of a presentation she gives to google workers, it's a good intro. Not trying to spam here, just posting about it because it's helped me a lot.
Posted by tom0s
4th Jul
0 Votes
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false positive?
Pain usually tells us of danger. Like burns, broken bones, bleeding. In this case, could the pain be false positives of dangers that aren't their? Could a pain sufferer's physical health be fine, but for some reason the brain thinks it's not, and fire off false positive pain signals?
Posted by wfang173
6th Jul
0 Votes
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What about the DEA
The DEA often goes after people with chronic pain and the doctors who treat them. They limit the pain meds that can be prescribed. I wonder if this might vindicate some of these doctors and patients.
Posted by halomar1970
7th Jul
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