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Gates’ $10 billion vaccine pledge will yield ‘amazing effect’ on child mortality

By | February 3, 2010, 4:00 AM PST

Last week Bill & Melinda Gates announced that their foundation would commit $10 billion over the next decade to help research, develop and deliver vaccines for the world’s poorest countries.

By significantly scaling up the delivery of life-saving vaccines in developing countries to 90 percent coverage—including new vaccines to prevent severe diarrhea and pneumonia—the model suggests that we could prevent the deaths of 7.6 million children under 5 before 2019. The foundation also estimates that an additional 1.1 million children could be saved with the rapid introduction of a malaria vaccine beginning in 2014, bringing the total number of potential lives saved to 8.7 million.

Dr. Jean-Marie Okwo-Bele is the director of the World Health Organization Department of Immunization, Vaccines and Biologicals and is responsible for strategic direction, coordination and management of immunization activities. He called me yesterday from Geneva to answer a few questions about the Gates’ pledge.

What is the significance of the announcement by Bill and Melinda Gates?

This is a really great investment. As our [Director-General] said, an unprecedented one that will certainly help us advance our cause. The Gates have been investing in vaccinations over the last decade or so, and committing this support for the next 10 years means they strongly believe –as we do—in the value of these interventions and the impact of vaccinations. [The funding announced last week is in addition to the $4.5 billion that the Gates Foundation has already committed to vaccine research, development and delivery.]

Ten billion is a lot of money.

Yes, $10 billion is a lot of money. But you may want to know the estimates we did a few years back on achieving some of the globally established goals for immunization. From the 72 poorest countries between 2006 and 2015, we would need close to $34 billion. So getting closer to 2015, $4 billion per year is needed for all expenses including staff salaries, infrastructure, research. It’s a great contribution, but the work ahead is truly, truly huge, not only in terms of vaccines but insuring that they are actually delivered to the right people in some of those countries with weak delivery systems.

What vaccines are you focused on?

We’ve had tremendous progress with measles—an 80 percent reduction over the last 10 years. But to sustain this, newborns and infants require vaccination. In addition to measles mortality reduction efforts, you have polio eradication (as we have done with the smallpox in the ‘70s), meningitis outbreaks in West Africa, some of the new vaccines for childhood diarrhea and pneumonia… you bring all this together, it’s a big effort.

What will the money cover, besides vaccines?

It will contribute to [everything from] vaccine research to vaccine delivery. We would hope that some of the money would help facilitate the development of vaccines that are stable and can be readily used in developing countries. Vaccines must be refrigerated, and we could improve on the technology of some of the equipment to store the vaccines. There are many areas of research. As we are talking now, we have product available and country demand and means to deliver.

How will this affect child mortality?

It will have an amazing effect. One of the recent key successes in child mortality reduction is with measles. It was killing nearly 800,000 kids, and now we’re talking about a couple hundred thousand. That level of reduction is because of vaccination. But that’s just specific measles mortality. When one delivers measles vaccine, one brings along other intervention—like mosquito bed nets, deworming tablets that can reduce the infection due to malaria and reduce malnutrition. So the indirect effect of measles vaccination also shows success. As we go forward in the next 10 years, we’ve developed a strategy with UNICEF: When [one delivers] a new vaccine against pneumonia or diarrhea, one must bring along other child health intervention or programs so we can maximize any intervention with children. We see this as a trigger to accelerate mortality reduction in children in general.

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Melanie D.G. Kaplan

About Melanie D.G. Kaplan

Melanie D.G. Kaplan is a contributing writer for SmartPlanet.

Melanie D.G. Kaplan

Melanie D.G. Kaplan

Contributing Writer

Melanie D.G. Kaplan is a regular contributor to The Washington Post and Nomad Edition's Good Dog and has written for The New York Times, National Geographic Traveler and People. She holds degrees from Syracuse University and Columbia University's Graduate School of Journalism. She is based in Washington, D.C.

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Melanie D.G. Kaplan

Melanie D.G. Kaplan

In addition to working as a journalist, Melanie keeps the dog food fund flush with occasional consulting jobs. In the unusual event that her writing mentions a company or organization for which she has provided editorial services, she will disclose that fact. She will do the same should she cover any companies in which she holds investments.

She writes for SmartPlanet and is not an employee of CBS.

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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
Not trying to sound harsh, but we have to learn to control the human population as a whole on this planet. As we continue to allow the populations to explode, including by providing more vaccines, the population explosion is causing global warming to increase, natural resources to be depleted, and non-renewable resources to be used up faster.

Shouldn't we worry about population control, renewable energy, and controlling global warming before we significantly increase the strain on the planet by allowing millions more to survive?

I know this sounds very harsh, but really, no one including myself wants to see someone suffer or die needlessly, but lets start facing the facts and set priorities properly.

We need to stop using non-renewable resources completely, learn to control the human population at a level that is sustainable (at regional and global levels), then worry about stamping out disease.

I applaud the efforts of the Gates', but let?s work not put he cart in front of the horse! They should donate 10 Billion to provide renewable energy to the world. I think it will take a massive war or starvation to occur in one or more large developed nations before we seriously address controlling population growths.
Posted by rmark@...
3rd Feb 2010
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
I think the donation is extremely generous, but what's going to happen to the 8.5 people who survive?

Are they going to get enough food to eat and clean water to drink? The lack of clean water is the the primary reason for diarrhea (and I'm sure many other diseases/issues as well). Unless these issues are resolved, the long term prognosis is still bleak.
Posted by jlongino@...
3rd Feb 2010
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
What is the effect of vaccines on malnourished children? Aren't they tested on full-weight, healthy children of different ethnicities? According to medica literature, vaccines should not be administered to sick children whose immune systems are already challenged. Who will test these children first?

Will any medical follow-up will be done in these countries? If a cluster of children become injured by the vaccine -- which may takes weeks to fully manifest -- will Gates' fund compensate them?

Will food and clean water be equally prioritized in these at-risk communities? Many questions remain unanswered about Bill Gates' circular investing.
Posted by nhokkanen
3rd Feb 2010
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Gates' $10 billion vaccine pledge will yield 'amazing effect' on Bill Gate!
Exactly, any ancient urban center sustained itself, grew and prospered due to the fundamentals of bringing in clean water and removing wasted without the two ever coming into contact with the other.

Money should be spent on the infrastructure of water and sanitation, electricity etc; social collective organization, development, economy and most immortally the wealth generated from the indigenous natural resources need to distributed in a more equitable away. This will lead the poor out of poverty, sustain them while naturally controlling population. After all how did any western European country do it? Vaccines are not necessary when these things have been done or else vaccines will become the crutch of the poor and unfortunately as it has been proven, will leed to more ailments and death not a reduction.
Posted by mario@...
3rd Feb 2010
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
I am a physician who works with Immigration for various countries.

I would hope with the plan for these vaccines, there would be a
way to document who gets what vaccines, and at what ages.

There is not, at this time, including with the WHO a program to
follow the vaccine applications, since most vaccines are a series
of vaccines, and if there is it is not available over the
internet.

It is ironic that Mr. Gates, has contributed technically so much
to the development of Computers, and the Internet, and now it
seems to vaccine availability for the poor. Many of these poor
children, if they survive, will immigrate to other countries, or
need documented information of what vaccines were applied to him
(or her). To say that thousands of certain vaccines were applied
to a specific country, and the illness has improved in that
country, does not help the individual when he or she develops,
without knowing the personal medical health. The personal medical
health of the individual is lost to poverty and time.

My suggestion:

A simple electronic record on the internet for each person on the
planet, that contains, name and date of birth, dates and types of
vaccines applied, would be of tremendous help.

Some states have such a program, but even in the United States,
such a program does not exist. One is needed, that would include
every person on the planet.

Confidentiality would not be an issue for vaccines.
I cannot see why any country would not participate in such a
program.

Fernando Partida-Ruesga, MD
dpartida@frontiernet.net
Posted by Fpartida
4th Feb 2010
+1 Vote
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Clean water please!
I concur with Mario.

Let's start with clean water and sanitation. That would prevent a huge portion of sickness from ever happening.
Posted by pwatson
6th Feb 2010
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@ #1
I wondered how long it would take one of the "people evil, earth good" crowd to trot out the greenie genocide line. You genocidalists so have missed the point of why God created Earth in the first place, haven't you? We are not here for the Earth, IT is here for US. And God directed us right from the get-go to multiply and FILL the earth, not squash ourselves into socialist communes run by Satan-worshipers...
Posted by EndGame666
8th Feb 2010
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
I know that if we are able to help third world countries benefit from progressing their countries we will spend less in the future in aid. It really does effect us when you think about the lifestyles third world countries have to live. Someone has to do something, or we will just have to continue to spend money that we need here in the states to help the less fortunate out over and over again.
Posted by Eyveneen
17th Feb 2010
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
Did you know that the disease myalgic encephalomyelitis (chronic fatigue
syndrome) is estimated to cost the US economy at least $25 billion dollars a
year, in terms of the loss to the workforce, as well as medical care.

About 0.2% of the US population are severely incapacitated with ME/CFS,
yet this is one of the most overlooked, ignored and unconsidered health
problems in our own county.

Probably just a 1 or 2 billion dollars pumped into research for a cure for
ME/CFS would yields results very quickly, and then on having a cure, we
would save the US $25 billion dollars a year henceforth (money which could
then be direct to fixing other health problems).

The research budget in ME/CFS is extremely small, in the order of millions a
year, which given the large scale and severe economic costs of ME/CFS, is
a paltry amount.
Posted by Hip777
1st Feb 2011
+1 Vote
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RE: Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mortality
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14th Apr
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Gates' $10 billion vaccine pledge will yield 'amazing effect' on child mort
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