Follow this blog:
RSS

Dreaming of Jurassic Park? DNA says thanks, but no thanks

By | October 11, 2012, 4:11 AM PDT

Sorry to burst your bubble, but Jurassic Park will have to remain a daydream — thanks to a new DNA study.

Who doesn’t remember the film Jurassic Park? Raptors and a Triceratops, rebellious DNA fueled by mutated frog codes, the branded lunchboxes and enraptured paleontologists. It was meant to teach us that messing with nature could bring back the monsters of the past — but we could all still dream.

Now, however, a study has revealed just how long dinosaur DNA lasts — and its longer than we thought, but not long enough.

521 years is the half-life of a DNA strand, according to work published in Proceedings of the Royal Society. A team of palaeogeneticists led by Morten Allentoft at the University of Copenhagen and Michael Bunce at Murdoch University in Perth, Australia, conducted the study.

Examining 158 leg bones that belong to three species of an extinct giant bird called a moa, each DNA-containing fossil was between 600 and 8,000 years old. The samples, found in New Zealand, were used to calculate degrees of DNA degradation — and therefore what could be recovered feasibly.

By comparing the specimens’ ages and degrees of degradation, the scientists calculated DNA’s half-life. After 521 years, half of the bonds that bind nucleotides together break, and in another 521 they would break again, and so on.

What does this mean? No Jurassic Park for you. Even if a bone was preserved at the ideal level of −5 ºC, almost every bond would break before the end of 6.8 million years. But after approximately 1.5 million years, the DNA would be unreadable. Not much luck for 65 million year-old bones then.

“This confirms the widely held suspicion that claims of DNA from dinosaurs and ancient insects trapped in amber are incorrect,” says Simon Ho, an evolutionary biologist at the University of Sydney in Australia. “However, although 6.8 million years is nowhere near the age of a dinosaur bone — which would be at least 65 million years old — We might be able to break the record for the oldest authentic DNA sequence, which currently stands at about half a million years.”

Whether these results would be the same in environments including frost and caves remains to be seen. Inerestingly, age differences only accounted for 38.6 percent of variation in moa-bone DNA, which suggests that other factors come into play — including soil chemistry, excavation techniques and potentially even the time of year the animal died.

Related:

Start your week smarter with our weekly e-mail newsletter. It's your cheat sheet for good ideas. Get it.

Charlie Osborne

About Charlie Osborne

Charlie Osborne is a contributing editor for SmartPlanet.

Charlie Osborne

Charlie Osborne

Contributing Editor

Charlie Osborne is a freelance journalist and graphic designer based in London. In addition to SmartPlanet, she also writes the iGeneration column for business technology website ZDNet. She holds degrees in medical anthropology from the University of Kent.

Follow her on Twitter.

Charlie Osborne

Charlie Osborne

Charlie Osborne does not have financial holdings that would influence how or what she covers.

She writes for SmartPlanet and is not an employee of CBS.

If you liked this, don't miss...
10
Comments

Join the conversation!

Follow via:
RSS
0 Votes
+ -
Jurassic DNA Halflife
Be interesting to see the details of this study. I would tend to doubt the results as a generality. After all, protein should behave similarly since amide hydrolysis is not that dissimilar from phosphodiester hydrolysis kinetically. However, Jack Horner's grad students identified intact collagen in T. rex leg bones. Just sayin'...
Posted by smfieldssr@...
11th Oct
-1 Votes
+ -
Young Bones
I would not give up hope. They make a wrong assumption. The dinosaur/dragon bones are only hundreds of years old.
Posted by NewKreation
11th Oct
-2 Votes
+ -
young bones
idiot.
Posted by bookmanpc
11th Oct
0 Votes
+ -
DNA's "half-life"
"By comparing the specimens ages and degrees of degradation, the scientists calculated DNAs half-life. After 521 years, half of the bonds that bind nucleotides together break, and in another 521 they would break again, and so on."

better as
By comparing the specimens ages and degrees of degradation, the scientists calculated DNAs "half-life". After 521 years, half of the bonds that bind nucleotides together will have broken, and in another 521 half of those left intact would have themselves broken, and so on. Even beaking a few bonds (i.e. in the first few years) may well render the DNA "useless".

(c.f.radioactive decay)
Posted by p.bradfield
11th Oct
+2 Votes
+ -
Interesting data...faulty conclusion.
While it is extremely unlikely that functional DNA strands from 100 million year old samples can be extracted and used directly, this is far from the only methodology to recreate an ancient life-form.

Start with any descendant species. The DNA will contain many segments which it inherited.

Proteins do break down, but the breakdown products can be used to extrapelate back to the original molecules.

A sufficiently large specimen, say several tons, frozen under the Antarctic Ice, would potentially yield a usable sample, and almost certainly would yeild a statistically large enough sample to recreate the original DNA...a couple miles of ice prevents an awful lot of high energy particles from reaching the sample.

We cannot prove with absolute certainty that such lifeforms haven't survived somewhere--perhaps not on Earth.

In the absolute worst case, having a decent idea of the genome expression from the fossil record, and assuming we learn to understand how to manipulate DNA, we can produce individuals and/or species 'replicas' which may or may not be identical to the original species, but would represent how such species probably looked and acted based upon our knowledge and speculation.

I'd bet that at the very least, someone will succeed with the last possibility...not this decade nor next, but probably within 500-1000 years barring major setbacks (like asteroid strikes, global or our species destruction.) Possibly by the end of the current century.
Posted by wizoddg
11th Oct
+1 Vote
+ -
Dreaming of Jurassic Park?...
But reviving a dinosaur nowadays would be awfully impractical, wouldn't it? what could we do with it? where would we keep it? I don't think it could be a good idea to have one as a pet at home (in a studio apartment?) it sounds rather messy, what about neighbors complaints?
At lunch time we'll have a big dilemma: A live cow? several dozen rabbits? three or four goats? And the expense!
And how do we convince the animal to take a shower?
There are too many "Buts"
They look much nicer in film, and we don't have to take care of them (like with babies).
Posted by David Traversa
11th Oct
+3 Votes
+ -
Not all break at the same point
The DNA strands don't all break at the same points, do they? If enough fragments could be scavenged from the same critter, they could be arranged so that fragments from some strands bridge the breaks in others, ultimately yielding the entire code, no?
Posted by lmarks@...
11th Oct
0 Votes
+ -
Shotgun approach
Isn't that basically how the "shotgun" approach works to sequence DNA? They sequence bits and pieces, then "glue" them together.
But after 10 half-lives, there wouldn't be many long pieces left. I suppose if you had enough DNA, you might get lucky and find enough long pieces still intact.
BUT! If the half-life is only 521 years, then 10 half-lives is only 5210 years. A million years is like 2000 half-lives. So 65 million years is 100,000 half-lives. You would need to sort through an ENORMOUS amount of DNA before you'd find the necessary intact chains. I think that qualifies as a sisyphean task.
Posted by dmm99
16th Oct
-2 Votes
+ -
super particle humans of sorts
those dinosaurs have evolved to HUMANS ! look at most humans now, has traits like those. let humans now evolve to super humans, light particles so we can be free in space.

just im waiting that all monkeys should evolve into something more human (DIDNT THEY YET ? ) . see no monkies, and see no humans(there gone particles).

this article kills the evolution theory.
Posted by ilovesards@...
11th Oct
0 Votes
+ -
This post is an embarrassment
@ilovesards: Are you drunk? institutionalized? a bot?
Posted by dmm99
16th Oct
Join the conversation
Formatting +
BB Codes - Note: HTML is not supported in forums
  • [b] Bold [/b]
  • [i] Italic [/i]
  • [u] Underline [/u]
  • [s] Strikethrough [/s]
  • [q] "Quote" [/q]
  • [ol][*] 1. Ordered List [/ol]
  • [ul][*] · Unordered List [/ul]
  • [pre] Preformat [/pre]
  • [quote] "Blockquote" [/quote]

Join the SmartPlanet community and join the conversation! Signing up is fast and free. Don't wait -- we want to hear your opinion!